Exploring the Multifaceted Landscape of MASLD: A Comprehensive Synthesis of Recent Studies, from Pathophysiology to Organoids and Beyond

A Soto, C Spongberg, A Martinino, F Giovinazzo - Biomedicines, 2024 - mdpi.com
Non-alcoholic fatty liver disease (NAFLD) is a widespread contributor to chronic liver
disease globally. A recent consensus on renaming liver disease was established, and …

Serum metabolomic profiling unveils distinct sex-related metabolic patterns in NAFLD

C Fotakis, IP Kalafati, AI Amanatidou… - Frontiers in …, 2023 - frontiersin.org
Objective Obesity poses an increased risk for the onset of Nonalcoholic fatty liver disease
(NAFLD). The influence of other factors, such as sex in the incidence and severity of this liver …

Identification and validation of disulfidptosis-associated molecular clusters in non-alcoholic fatty liver disease

X Yu, Z Guo, Z Fang, K Yang, C Liu, Z Dong… - Frontiers in …, 2023 - frontiersin.org
Objective: Non-alcoholic fatty liver disease (NAFLD) is the most prevalent liver disease in
the world, and its pathogenesis is not fully understood. Disulfidptosis is the most recently …

NPC1L1 Plays a Novel Role in Nonalcoholic Fatty Liver Disease

CL Xu, F Fu, Y She, CB Xu - ACS omega, 2023 - ACS Publications
Niemann-Pick C1-Like 1 (NPC1L1) is a key protein in the transport of cholesterol, which
exists in the brush marginal membrane of the intestinal epithelial cells and the timid duct …

The role of ElastPQ in assessing liver stiffness for non-alcoholic fatty liver disease in patients treated with atypical antipsychotic drugs

L Sun, N Li, L Zhang, J Chen - Neuropsychiatric Disease and …, 2023 - Taylor & Francis
Objective To evaluate the role of elastography point quantification (ElastPQ) for the
quantitative assessment of stiffness in the fatty liver disease in mental disorder patients and …

Causal relationship between depression and metabolic dysfunction-associated steatotic liver disease: a bidirectional Mendelian randomized study

W Liang, K Zhong, T Lai, Y Zeng, Z Huang… - Frontiers in …, 2024 - frontiersin.org
Background With the global rise in obesity, metabolic dysfunction-associated steatotic liver
disease (MASLD) has emerged as the most common chronic liver disease. Concurrently …

[HTML][HTML] Global research on portal vein thrombosis and liver transplantation: A bibliometric and visualized study

L Zhong, TT Ren, L Shi, Q Deng, L Hong, C Yu, T Yun… - Medicine, 2023 - journals.lww.com
In recent years, the association between portal vein thrombosis and liver transplantation has
extensive attention from physicians worldwide. However, there is no available literature on …

[PDF][PDF] The diagnostic utility of FIB-4 as a non-invasive tool for liver fibrosis scoring among NAFLD patients: a retrospective cross-sectional study.

J Amer, M Alnees, M Salameh… - European Review for …, 2024 - europeanreview.org
OBJECTIVE: Liver biopsy is the gold standard method to evaluate patients with non-
alcoholic fatty liver disease (NAFLD). However, due to its several limitations and …

Liver-innervating vagal sensory neurons play an indispensable role in the development of hepatic steatosis and anxiety-like behavior in mice fed a high-fat diet

J Hwang, J Okada, JE Pessin, SC Chua Jr… - bioRxiv, 2024 - biorxiv.org
Abstract Background and Aims The visceral organ-brain axis, mediated by vagal sensory
neurons in the vagal nerve ganglion, is essential for maintaining various physiological …

Genetic associations of dimensional autistic phenotypes

T Eriksson, C Nakamori, K Iwamoto - bioRxiv, 2023 - biorxiv.org
Since there is a large variation in the symptoms shown by persons affected with ASD,
analyzing genetics data using a case-control design is not straightforward. To avoid the …