Risk and Prognostic Factors for BRAFV600E Mutations in Papillary Thyroid Carcinoma

X Wei, X Wang, J Xiong, C Li, Y Liao… - BioMed Research …, 2022 - Wiley Online Library
Background. Over the past ten years, the incidence rate of papillary thyroid carcinoma (PTC)
worldwide has been increasing rapidly year by year, with the incidence rate increasing 6 …

Clinical use of molecular data in thyroid nodules and cancer

AS Alzahrani - The Journal of Clinical Endocrinology & …, 2023 - academic.oup.com
Over the past 3 decades, advances in the molecular genetics of thyroid cancer (TC) have
been translated into diagnostic tests, prognostic markers, and therapeutic agents. The main …

Associations between BRAFV600E and prognostic factors and poor outcomes in papillary thyroid carcinoma: a meta-analysis

C Liu, T Chen, Z Liu - World journal of surgical oncology, 2016 - Springer
Background The objective of this study is to perform a meta-analysis to evaluate the
associations between the BRAF V600E mutation status and aggressive clinicopathological …

Relationship between BRAF V600E and clinical features in papillary thyroid carcinoma

C Yan, M Huang, X Li, T Wang… - Endocrine connections, 2019 - ec.bioscientifica.com
Objective To investigate the mutant status of BRAF gene and analyze its relationship to
epidemiological risk factors and clinical outcomes among patients with papillary thyroid …

Comparison of the clinicopathologic features and prognosis of bilateral versus unilateral multifocal papillary thyroid cancer: an updated study with more than 2000 …

W Wang, X Su, K He, Y Wang, H Wang, H Wang… - Cancer, 2016 - Wiley Online Library
BACKGROUND Bilaterality is common in papillary thyroid cancer (PTC), but its clinical and
prognostic implications are still controversial, and it remains unclear whether its behavior is …

A meta-analysis of prognostic roles of molecular markers in papillary thyroid carcinoma

HG Vuong, UNP Duong, AMA Altibi… - Endocrine …, 2017 - ec.bioscientifica.com
The prognostic role of molecular markers in papillary thyroid carcinoma (PTC) is a matter of
ongoing debate. The aim of our study is to investigate the impact of RAS, BRAF, TERT …

Molecular markers involved in tumorigenesis of thyroid carcinoma: focus on aggressive histotypes

GC Penna, F Vaisman, M Vaisman… - … and genome research, 2017 - karger.com
Thyroid cancer derived from follicular cells (TCDFC) comprises well-differentiated (papillary
and follicular) carcinoma, poorly differentiated carcinoma, and anaplastic carcinoma …

[HTML][HTML] Predictors for central lymph node metastases in CN0 papillary thyroid microcarcinoma (mPTC): a retrospective analysis of 1304 cases

Q Zhang, Z Wang, X Meng, QY Duh, G Chen - Asian Journal of Surgery, 2019 - Elsevier
Background Presence of lymph node metastases increases the risk of recurrence, but
prophylactic central neck node dissection for patients with micropapillary thyroid cancer …

Association of TERT promoter mutation, but not BRAF mutation, with increased mortality in PTC

JR George, YC Henderson, MD Williams… - The Journal of …, 2015 - academic.oup.com
Context: Papillary thyroid carcinoma (PTC) carrying the BRAF mutation has been reported to
be associated with high recurrence and potentially increased mortality. PTC carrying the …

BRAF and NRAS Mutations in Papillary Thyroid Carcinoma and Concordance in BRAF Mutations Between Primary and Corresponding Lymph Node Metastases

N Fakhruddin, M Jabbour, M Novy, H Tamim… - Scientific reports, 2017 - nature.com
Concordance between mutations in the primary papillary thyroid carcinoma (PTC) and the
paired x lymph node metastasis may elucidate the potential role of molecular targeted …