[HTML][HTML] Dietary polyphenols and non-alcoholic fatty liver disease

L Abenavoli, T Larussa, A Corea, AC Procopio… - Nutrients, 2021 - mdpi.com
Non-alcoholic fatty liver disease (NAFLD), which is emerging as a major public health issue
worldwide, is characterized by a wide spectrum of liver disorders, ranging from simple fat …

[HTML][HTML] NLRP3 inflammasome and pyroptosis in liver pathophysiology: The emerging relevance of Nrf2 inducers

L Hurtado-Navarro, D Angosto-Bazarra, P Pelegrín… - Antioxidants, 2022 - mdpi.com
Inflammasomes, particularly the nucleotide-binding oligomerization domain, leucine-rich
repeat, and pyrin domain containing 3 (NLRP3) inflammasome, apparently serve as crucial …

Ameliorative effects of chlorogenic acid on alcoholic liver injury in mice via gut microbiota informatics

H Zhu, W Jiang, C Liu, C Wang, B Hu, Y Guo… - European Journal of …, 2022 - Elsevier
Chlorogenic acid (CGA) is a functional phenolic acid widely used in food and medicine-
related fields. It has been proved to be effective in the treatment of alcoholic liver disease …

[HTML][HTML] The regulatory effects of citrus peel powder on liver metabolites and gut flora in mice with non-alcoholic fatty liver disease (NAFLD)

M Hu, L Zhang, Z Ruan, P Han, Y Yu - Foods, 2021 - mdpi.com
Gannan navel orange and Jinggang pomelo, belonging to the genus Citrus, are good
sources of phenolic compounds, which are mainly concentrated in the peel. These phenolic …

[HTML][HTML] Targeting Oxidative Stress with Polyphenols to Fight Liver Diseases

IF Machado, RG Miranda, DJ Dorta, AP Rolo… - Antioxidants, 2023 - mdpi.com
Reactive oxygen species (ROS) are important second messengers in many metabolic
processes and signaling pathways. Disruption of the balance between ROS generation and …

[HTML][HTML] Kaempferol suppresses carbon tetrachloride-induced liver damage in rats via the MAPKs/NF-κB and AMPK/Nrf2 signaling pathways

C Lee, S Yoon, JO Moon - International Journal of Molecular Sciences, 2023 - mdpi.com
Oxidative stress plays a critical role in the development of liver disease, making antioxidants
a promising therapeutic approach for the prevention and management of liver injuries. The …

[HTML][HTML] Natural products in attenuating renal inflammation via inhibiting the NLRP3 inflammasome in diabetic kidney disease

Y Wang, Z Sui, M Wang, P Liu - Frontiers in Immunology, 2023 - frontiersin.org
Diabetic kidney disease (DKD) is a prevalent and severe complications of diabetes and
serves as the primary cause of end-stage kidney disease (ESKD) globally. Increasing …

Pharmacological action of quercetin against testicular dysfunction: A mini review

DE Rotimi, TD Olaolu, OS Adeyemi - Journal of Integrative Medicine, 2022 - Elsevier
The testis is an immune-privileged organ susceptible to oxidative stress and inflammation,
two major factors implicated in male infertility. A reduction in the concentration and activities …

Effect of phenolic compounds on human health

E González-Burgos, MP Gómez-Serranillos - Nutrients, 2021 - mdpi.com
This book, based on a Special Issue of Nutrients, contains a total of 12 papers (8 original
research and 4 reviews) on the effect of phenolic compounds on human health. The …

Protective effects of E Se tea extracts against alcoholic fatty liver disease induced by high fat/alcohol diet: In vivo biological evaluation and molecular docking study

Y Wang, Z Fan, M Yang, Y Wang, J Cao, A Khan, Y Liu… - Phytomedicine, 2022 - Elsevier
Background: With the development of economy and increased workload, chronic a high-
fat/alcohol diet intake may lead to alcoholic fatty liver disease (AFLD), which is considered …