A review of current trends with type 2 diabetes epidemiology, aetiology, pathogenesis, treatments and future perspectives

J Reed, S Bain, V Kanamarlapudi - Diabetes, Metabolic Syndrome …, 2021 - Taylor & Francis
Abstract Type 2 diabetes (T2D), which has currently become a global pandemic, is a
metabolic disease largely characterised by impaired insulin secretion and action. Significant …

Why primary obesity is a disease?

A De Lorenzo, S Gratteri, P Gualtieri… - Journal of translational …, 2019 - Springer
Obesity must be considered a real pathology. In the world wide, obesity represent one of the
major public health issue associated with increased morbidity and mortality. Overweight or …

American Association of Clinical Endocrinologists and American College of Endocrinology comprehensive clinical practice guidelines for medical care of patients with …

WT Garvey, JI Mechanick, EM Brett, AJ Garber… - Endocrine Practice, 2016 - Elsevier
Objective Development of these guidelines is mandated by the American Association of
Clinical Endocrinologists (AACE) Board of Directors and the American College of …

Interleukin-6 and C-reactive protein, successful aging, and mortality: the PolSenior study

M Puzianowska-Kuźnicka, M Owczarz… - Immunity & …, 2016 - Springer
Background In the elderly, chronic low-grade inflammation (inflammaging) is a risk factor for
the development of aging-related diseases and frailty. Using data from several thousand …

Relation of smoking with total mortality and cardiovascular events among patients with diabetes mellitus: a meta-analysis and systematic review

A Pan, Y Wang, M Talaei, FB Hu - Circulation, 2015 - Am Heart Assoc
Background—The prevalence of smoking in diabetic patients remains high, and reliable
quantification of the excess mortality and morbidity risks associated with smoking is …

Relationship among body fat percentage, body mass index, and all-cause mortality

R Padwal, SR Majumdar, WD Leslie - Annals of internal medicine, 2016 - acpjournals.org
TO THE EDITOR: Financial incentives can reinforce consumer behavior (for example,
offering money back for using a specific credit card), and these procedures are gaining …

Muscle mass, BMI, and mortality among adults in the United States: A population-based cohort study

MK Abramowitz, CB Hall, A Amodu, D Sharma… - PloS one, 2018 - journals.plos.org
Background The level of body-mass index (BMI) associated with the lowest risk of death
remains unclear. Although differences in muscle mass limit the utility of BMI as a measure of …

From the BMI paradox to the obesity paradox: the obesity–mortality association in coronary heart disease

AS Antonopoulos, EK Oikonomou… - Obesity …, 2016 - Wiley Online Library
Despite a strong association between body weight and mortality in the general population,
clinical evidence suggests better clinical outcome of overweight or obese individuals with …

[HTML][HTML] Exploring the impact of obesity on skeletal muscle function in older age

PT Morgan, B Smeuninx, L Breen - Frontiers in Nutrition, 2020 - frontiersin.org
Sarcopenia is of important clinical relevance for loss of independence in older adults. The
prevalence of obesity in combination with sarcopenia ('sarcopenic-obesity') is increasing at …

Effectiveness of combined exercise in people with type 2 diabetes and concurrent overweight/obesity: A systematic review and meta-analysis

X Zhao, Q He, Y Zeng, L Cheng - BMJ open, 2021 - bmjopen.bmj.com
Objective To synthesise the available scientific evidence on the effects of combined exercise
on glycaemic control, weight loss, insulin sensitivity, blood pressure and serum lipids among …