We review the characteristics of osteoblast differentiation and bone matrix synthesis. Bone in
air breathing vertebrates is a specialized tissue that developmentally replaces simpler solid …

Stem cell fate is closely intertwined with microenvironmental and endogenous cues within
the body. Recapitulating this dynamic environment ex vivo can be achieved through …

The development of biomaterials, stem cells and bioactive factors has led to cartilage tissue
engineering becoming a promising tactic to repair cartilage defects. Various polymer three …

Articular cartilage is a highly specialized tissue whose remarkable properties of
deformability, resistance to mechanical loading, and low-friction gliding are essential to joint …

Tremendous advances in tissue engineering and regenerative medicine have revealed the
potential of fabricating biomaterials to solve the dilemma of bone and articular defects by …

Background Osteoarthritis (OA), a prevalent degenerative disease characterized by
degradation of extracellular matrix (ECM), still lacks effective disease-modifying therapy …

Background The purpose of this study is to investigate the clinical effects of platelet-rich
plasma (PRP) and adipose-derived mesenchymal stem cell (MSC) as the fundamental …

Mesenchymal stem cells (MSCs) are self-renewable cells capable for multilineage
differentiation and immunomodulation. MSCs are able to differentiate into all cell types of …

The present work investigated the use of biodegradable hydrogel composite scaffolds,
based on the macromer oligo (poly (ethylene glycol) fumarate)(OPF), to deliver growth …

Background Osteoarthritis (OA) is a degenerative joint disease affecting approximately 27
million Americans, and even more worldwide. OA is characterized by degeneration of …