The diagnostic and therapeutic potential of galectin-3 in cardiovascular diseases

G Sygitowicz, A Maciejak-Jastrzębska, D Sitkiewicz - Biomolecules, 2021 - mdpi.com
Galectin-3 plays a prominent role in chronic inflammation and has been implicated in the
development of many disease conditions, including heart disease. Galectin-3, a regulatory …

Chimeric galectin-3 and collagens: Biomarkers and potential therapeutic targets in fibroproliferative diseases

P Nangia-Makker, V Hogan, V Balan, A Raz - Journal of Biological …, 2022 - ASBMB
Fibrosis, stiffening and scarring of an organ/tissue due to genetic abnormalities,
environmental factors, infection, and/or injury, is responsible for> 40% of all deaths in the …

Microglial Galectin3 enhances endothelial metabolism and promotes pathological angiogenesis via Notch inhibition by competitively binding to Jag1

ZY Zhou, TF Chang, ZB Lin, YT Jing, LS Wen… - Cell Death & …, 2023 - nature.com
Microglia were considered as immune cells in inflammation until their angiogenic role was
widely understood. Although the pro-inflammatory role of microglia in retinal angiogenesis …

A Review on the Immunological Response against Trypanosoma cruzi

G Macaluso, F Grippi, S Di Bella, V Blanda, F Gucciardi… - Pathogens, 2023 - mdpi.com
Chagas disease is a chronic systemic infection transmitted by Trypanosoma cruzi. Its life
cycle consists of different stages in vector insects and host mammals. Trypanosoma cruzi …

The role of galectin-3 in heart failure—the diagnostic, prognostic and therapeutic potential—where do we stand?

B Zaborska, M Sikora-Frąc, K Smarż… - International Journal of …, 2023 - mdpi.com
Heart failure (HF) is a clinical syndrome with high morbidity and mortality, and its prevalence
is rapidly increasing. Galectin-3 (Gal-3) is an important factor in the pathophysiology of HF …

Biomarkers and optical based biosensors in cardiac disease detection: early and accurate diagnosis

F Fathi, A Arabzadeh, A Mohammadzadeh - Analytical Methods, 2023 - pubs.rsc.org
Rapid and precise detection methods for the early-stage detection of cardiovascular
irregularities are crucial to stopping and reducing their development. Cardiovascular …

Functional mutation, splice, distribution, and divergence analysis of impactful genes associated with heart failure and other cardiovascular diseases

I Mhatre, H Abdelhalim, W Degroat, S Ashok… - Scientific reports, 2023 - nature.com
Cardiovascular disease (CVD) is caused by a multitude of complex and largely heritable
conditions. Identifying key genes and understanding their susceptibility to CVD in the human …

RNA methylations in cardiovascular diseases, molecular structure, biological functions and regulatory roles in cardiovascular diseases

W Zhou, C Wang, J Chang, Y Huang, Q Xue… - Frontiers in …, 2021 - frontiersin.org
Cardiovascular diseases (CVDs) are the leading cause of morbidity and mortality in the
world. Despite considerable progress in the diagnosis, treatment and prognosis of CVDs …

Biomarkers associated with cardiovascular disease in COVID-19

CC Kaufmann, A Ahmed, AL Burger, M Muthspiel… - Cells, 2022 - mdpi.com
Coronavirus disease-19 (COVID-19) emerged late December 2019 in the city of Wuhan,
China and has since spread rapidly all over the world causing a global pandemic. While the …

[HTML][HTML] Recent Advances on the Innate Immune Response to Coxiella burnetii

G Sireci, GD Badami, D Di Liberto, V Blanda… - Frontiers in Cellular …, 2021 - frontiersin.org
Coxiella burnetii is an obligate intracellular Gram-negative bacterium and the causative
agent of a worldwide zoonosis known as Q fever. The pathogen invades monocytes and …