Cancers make their own luck: theories of cancer origins

A Jassim, EP Rahrmann, BD Simons… - Nature reviews …, 2023 - nature.com
Cancer has been a leading cause of death for decades. This dismal statistic has increased
efforts to prevent the disease or to detect it early, when treatment is less invasive, relatively …

[HTML][HTML] Human papillomavirus vaccine against cervical cancer: Opportunity and challenge

R Wang, W Pan, L Jin, W Huang, Y Li, D Wu, C Gao… - Cancer letters, 2020 - Elsevier
Cervical cancer is one of the most common cancers threatening women's health, and the
persistent infection of high-risk human papillomavirus (HPV) is closely related to the …

DNA tumor virus oncogenes antagonize the cGAS-STING DNA-sensing pathway

L Lau, EE Gray, RL Brunette, DB Stetson - Science, 2015 - science.org
Cyclic guanosine monophosphate–adenosine monophosphate synthase (cGAS) detects
intracellular DNA and signals through the adapter protein STING to initiate the antiviral …

[HTML][HTML] Cross-roads in the classification of papillomaviruses

EM de Villiers - Virology, 2013 - Elsevier
Acceptance of an official classification for the family Papillomaviridae based purely on DNA
sequence relatedness, was achieved as late as 2003. The rate of isolation and …

An update on human papilloma virus vaccines: history, types, protection, and efficacy

Z Yousefi, H Aria, F Ghaedrahmati, T Bakhtiari… - Frontiers in …, 2022 - frontiersin.org
Human papillomavirus (HPV) is the most common sexually transmitted agent worldwide.
Early prevention with HPV vaccination is a safe and effective method against this disease …

Cancer and the immune system: basic concepts and targets for intervention

D Pardoll - Seminars in oncology, 2015 - Elsevier
A number of consensuses regarding cancer immunology have recently emerged from both
preclinical immunotherapy models and analysis of cancer patients. First and foremost, the …

Why do viruses cause cancer? Highlights of the first century of human tumour virology

PS Moore, Y Chang - Nature reviews cancer, 2010 - nature.com
The year 2011 marks the centenary of Francis Peyton Rous's landmark experiments on an
avian cancer virus. Since then, seven human viruses have been found to cause 10–15% of …

Papillomaviruses and cancer: from basic studies to clinical application

H Zur Hausen - Nature reviews cancer, 2002 - nature.com
Links between human papillomaviruses (HPVs) and cervical cancer were first suspected
almost 30 years ago. DNA of specific HPV types has since been found in almost all cervical …

[HTML][HTML] Papillomaviruses in the causation of human cancers—a brief historical account

H Zur Hausen - Virology, 2009 - Elsevier
Approximately 35 years ago a role of human papillomaviruses (HPV) in cervical cancer has
been postulated. Today it is well established that this very heterogeneous virus family …

The human papilloma virus-16 E7 oncoprotein is able to bind to the retinoblastoma gene product

N Dyson, PM Howley, K Münger, ED Harlow - Science, 1989 - science.org
Deletions or mutations of the retinoblastoma gene, RB1, are common features of many
tumors and tumor cell lines. Recently, the RB1 gene product, p105-RB, has been shown to …