Cancers make their own luck: theories of cancer origins
A Jassim, EP Rahrmann, BD Simons… - Nature reviews …, 2023 - nature.com
Cancer has been a leading cause of death for decades. This dismal statistic has increased
efforts to prevent the disease or to detect it early, when treatment is less invasive, relatively …
efforts to prevent the disease or to detect it early, when treatment is less invasive, relatively …
[HTML][HTML] Human papillomavirus vaccine against cervical cancer: Opportunity and challenge
R Wang, W Pan, L Jin, W Huang, Y Li, D Wu, C Gao… - Cancer letters, 2020 - Elsevier
Cervical cancer is one of the most common cancers threatening women's health, and the
persistent infection of high-risk human papillomavirus (HPV) is closely related to the …
persistent infection of high-risk human papillomavirus (HPV) is closely related to the …
DNA tumor virus oncogenes antagonize the cGAS-STING DNA-sensing pathway
L Lau, EE Gray, RL Brunette, DB Stetson - Science, 2015 - science.org
Cyclic guanosine monophosphate–adenosine monophosphate synthase (cGAS) detects
intracellular DNA and signals through the adapter protein STING to initiate the antiviral …
intracellular DNA and signals through the adapter protein STING to initiate the antiviral …
[HTML][HTML] Cross-roads in the classification of papillomaviruses
EM de Villiers - Virology, 2013 - Elsevier
Acceptance of an official classification for the family Papillomaviridae based purely on DNA
sequence relatedness, was achieved as late as 2003. The rate of isolation and …
sequence relatedness, was achieved as late as 2003. The rate of isolation and …
An update on human papilloma virus vaccines: history, types, protection, and efficacy
Human papillomavirus (HPV) is the most common sexually transmitted agent worldwide.
Early prevention with HPV vaccination is a safe and effective method against this disease …
Early prevention with HPV vaccination is a safe and effective method against this disease …
Cancer and the immune system: basic concepts and targets for intervention
D Pardoll - Seminars in oncology, 2015 - Elsevier
A number of consensuses regarding cancer immunology have recently emerged from both
preclinical immunotherapy models and analysis of cancer patients. First and foremost, the …
preclinical immunotherapy models and analysis of cancer patients. First and foremost, the …
Why do viruses cause cancer? Highlights of the first century of human tumour virology
The year 2011 marks the centenary of Francis Peyton Rous's landmark experiments on an
avian cancer virus. Since then, seven human viruses have been found to cause 10–15% of …
avian cancer virus. Since then, seven human viruses have been found to cause 10–15% of …
Papillomaviruses and cancer: from basic studies to clinical application
H Zur Hausen - Nature reviews cancer, 2002 - nature.com
Links between human papillomaviruses (HPVs) and cervical cancer were first suspected
almost 30 years ago. DNA of specific HPV types has since been found in almost all cervical …
almost 30 years ago. DNA of specific HPV types has since been found in almost all cervical …
[HTML][HTML] Papillomaviruses in the causation of human cancers—a brief historical account
H Zur Hausen - Virology, 2009 - Elsevier
Approximately 35 years ago a role of human papillomaviruses (HPV) in cervical cancer has
been postulated. Today it is well established that this very heterogeneous virus family …
been postulated. Today it is well established that this very heterogeneous virus family …
The human papilloma virus-16 E7 oncoprotein is able to bind to the retinoblastoma gene product
Deletions or mutations of the retinoblastoma gene, RB1, are common features of many
tumors and tumor cell lines. Recently, the RB1 gene product, p105-RB, has been shown to …
tumors and tumor cell lines. Recently, the RB1 gene product, p105-RB, has been shown to …