Human papillomavirus associated cervical lesion: pathogenesis and therapeutic interventions

J Ye, L Zheng, Y He, X Qi - MedComm, 2023 - Wiley Online Library
Human papillomavirus (HPV) is the most prevalent sexually transmitted virus globally.
Persistent high‐risk HPV infection can result in cervical precancerous lesions and cervical …

Human Papillomavirus Infection in Penile Cancer: Multidimensional Mechanisms and Vaccine Strategies

L Wei, K Huang, H Han, R Liu - International Journal of Molecular …, 2023 - mdpi.com
Penile cancer (PC) is a rare male malignant tumor, with early lymph node metastasis and
poor prognosis. Human papillomavirus (HPV) plays a key role in the carcinogenesis of PC …

Identification of transcriptionally‐active human papillomavirus integrants through nanopore sequencing reveals viable targets for gene therapy against cervical cancer

Q Zhao, S Yang, S Hao, Z Chen, L Tang… - Journal of Medical …, 2024 - Wiley Online Library
Integration of the human papillomavirus (HPV) genome into the cellular genome is a key
event that leads to constitutive expression of viral oncoprotein E6/E7 and drives the …

Cervical Cancer Stages, Human Papillomavirus Integration, and Malignant Genetic Mutations: Integrative Analysis of Datasets from Four Different Cohorts

FA Mohammed, KK Tune, M Jett, S Muhie - Cancers, 2023 - mdpi.com
Simple Summary This study provides a thorough examination of various aspects of cervical
cancer, using clinical and molecular datasets from four cohorts of patients across four …

Machine learning predicts metastatic progression using novel differentially expressed lncRNAs as potential markers in pancreatic cancer

H Alsharoh - medRxiv, 2023 - medrxiv.org
Pancreatic cancer (PC) is associated with high mortality overall. Recent literature has
focused on investigating long noncoding RNAs (lncRNAs) in several cancers, but studies on …

[HTML][HTML] The significance of human papillomavirus integration in carcinogenesis and the development of specific diagnostics and countermeasures

J Ying, G Wong, N Berthet - Global Translational Medicine, 2023 - accscience.com
Human papillomavirus (HPV) infection is associated with various tumors, notably in the
cervix, oropharyngeal region, and anus. As the disease progresses, integration of the viral …

Insights into tumor microenvironment and HPV integrations in cervical cancer pathogenesis revealed by single-cell transcriptome data

F Peng, X Zeng, Z Wang, Y Sha, RKK Leung, KCC LAI… - 2024 - researchsquare.com
Background HPV infection is prevalent among women, and can lead to severe diseases.
This study leverages single-cell RNA-sequencing (scRNA-seq), a cutting-edge technology …

An Investigation on the Intricacies of Epigenetic Modulations in the Pathogenesis of Human Papillomavirus-Associated Cervical Cancer: A Comprehensive Meta …

JC Cabello, MV Ras, KTN Tran, A Voytas - 2024 - openworks.mdanderson.org
Objective: To conduct a meta-analysis of the available and relevant literature on E1/E2
genes and their affect on the epigenetics of Human Papillomavirus caused uterine cervical …