The 2022 Nucleic Acids Research database issue and the online molecular biology database collection
DJ Rigden, XM Fernández - Nucleic acids research, 2022 - academic.oup.com
Abstract The 2022 Nucleic Acids Research Database Issue contains 185 papers, including
87 papers reporting on new databases and 85 updates from resources previously published …
87 papers reporting on new databases and 85 updates from resources previously published …
SLiMAn 2.0: meaningful navigation through peptide-protein interaction networks
V Reys, JL Pons, G Labesse - Nucleic Acids Research, 2024 - academic.oup.com
Among the myriad of protein–protein interactions occurring in living organisms, a substantial
amount involves small linear motifs (SLiMs) recognized by structured domains. However …
amount involves small linear motifs (SLiMs) recognized by structured domains. However …
Enhanced protein-protein interaction discovery via AlphaFold-Multimer
Accurately mapping protein-protein interactions (PPIs) is critical for elucidating cellular
functions and has significant implications for health and disease. Conventional experimental …
functions and has significant implications for health and disease. Conventional experimental …
Linear motifs regulating protein secretion, sorting and autophagy in Leishmania parasites are diverged with respect to their host equivalents
The pathogenic, tropical Leishmania flagellates belong to an early-branching eukaryotic
lineage (Kinetoplastida) with several unique features. Unfortunately, they are poorly …
lineage (Kinetoplastida) with several unique features. Unfortunately, they are poorly …
Brucella NpeA is a secreted Type IV effector containing an N-WASP-binding short linear motif that promotes niche formation
A Giménez, MG Del Giudice, PV López, F Guaimas… - Mbio, 2024 - Am Soc Microbiol
The modulation of actin polymerization is a common theme among microbial pathogens.
Even though microorganisms show a wide repertoire of strategies to subvert the activity of …
Even though microorganisms show a wide repertoire of strategies to subvert the activity of …
Best practices for the manual curation of intrinsically disordered proteins in DisProt
The DisProt database is a resource containing manually curated data on experimentally
validated intrinsically disordered proteins (IDPs) and intrinsically disordered regions (IDRs) …
validated intrinsically disordered proteins (IDPs) and intrinsically disordered regions (IDRs) …
Fast and scalable querying of eukaryotic linear motifs with gget elm
Abstract Motivation Eukaryotic linear motifs (ELMs), or Short Linear Motifs, are protein
interaction modules that play an essential role in cellular processes and signaling networks …
interaction modules that play an essential role in cellular processes and signaling networks …
Intrinsic Disorder in the Host Proteins Entrapped in Rabies Virus Particles
HN Ashraf, VN Uversky - Viruses, 2024 - mdpi.com
A proteomics analysis of purified rabies virus (RABV) revealed 47 entrapped host proteins
within the viral particles. Out of these, 11 proteins were highly disordered. Our study was …
within the viral particles. Out of these, 11 proteins were highly disordered. Our study was …
The substrate quality of CK2 target sites has a determinant role on their function and evolution
D Bradley, C Garand, H Belda, I Gagnon-Arsenault… - Cell Systems, 2024 - cell.com
Most biological processes are regulated by signaling modules that bind to short linear
motifs. For protein kinases, substrates may have full or only partial matches to the kinase …
motifs. For protein kinases, substrates may have full or only partial matches to the kinase …
Structured Tandem Repeats in Protein Interactions
J Mac Donagh, A Marchesini, A Spiga… - International Journal of …, 2024 - mdpi.com
Tandem repeats (TRs) in protein sequences are consecutive, highly similar sequence
motifs. Some types of TRs fold into structural units that pack together in ensembles, forming …
motifs. Some types of TRs fold into structural units that pack together in ensembles, forming …