Osteoarthritis (OA) remains the most challenging arthritic disorder, with a high burden of
disease and no available disease-modifying treatments. Symptomatic early-stage OA of the …

Understanding of the basis of osteoarthritis (OA) has seen some interesting advancements
in recent years. It has been observed that cartilage degeneration is preceded by …

Objective To estimate systematic and anatomic site–specific age‐standardized prevalence
rates (ASRs) and analyze the secular trends of osteoarthritis (OA) at global, regional, and …

Chondrocytes are the only cell type in normal cartilage. The pathological changes of
osteoarthritis (OA) mostly revolve around the apoptosis and dysfunction of chondrocytes …

Background Knee osteoarthritis is the most common joint disease and a major cause of
functional limitation and pain in adults. The aim of this literature review is to review the …

Osteoarthritis (OA) is a common disease that endangers millions of middle‐aged and elderly
people worldwide. Researchers from different fields have made great efforts and achieved …

To date, the application of oxygen-ozone (O2O3) therapy has significantly increased in the
common clinical practice in several pathological conditions. However, beyond the favorable …

Background Modern pharmacological research found that the chemical components of
Curcuma longa L. are mainly curcumin and turmeric volatile oil. Several recent randomized …

Purpose To test the hypothesis that artificial intelligence (AI) techniques can aid in
identifying and assessing lesion severity in the cartilage, bone marrow, meniscus, and …

Abstract Interleukin 18 (IL-18) promotes inflammation and apoptosis in chondrocytes,
thereby contributing to the development and progression of osteoarthritis (OA). Here, we …