Organoselenium and organotellurium compounds: toxicology and pharmacology

CW Nogueira, G Zeni, JBT Rocha - Chemical reviews, 2004 - ACS Publications
Organoselenium compounds have found such wide utility because of their effects on an
extraordinary number of very different reactions, including many carbon-carbon bond …

Biologically active compounds of semi-metals

T Řezanka, K Sigler - Studies in natural products chemistry, 2008 - Elsevier
Abstract Semi-metals, viz. boron, silicon, arsenic, selenium, tellurium and astatine form
organometal compounds, some of which are found in nature and have striking effects on the …

Hemolytic and genotoxic evaluation of organochalcogens in human blood cells in vitro

DB Santos, VPP Schiar, MW Paixão, DF Meinerz… - Toxicology in vitro, 2009 - Elsevier
This study investigated the hemolytic and genotoxic effect of different organoselenium and
organotellurium compounds in human blood cells, as simple tests for screening the toxicity …

Cytometric analysis of cytotoxicity of polyphenols and related phenolics to rat thymocytes: potent cytotoxicity of resveratrol to normal cells

A Fujimoto, Y Sakanashi, H Matsui… - Basic & Clinical …, 2009 - Wiley Online Library
The chemopreventive and chemotherapeutic actions of polyphenols and related phenolics
have received considerable attention since these compounds induce apoptosis in several …

Bisabololoxide A, one of the main constituents in German chamomile extract, induces apoptosis in rat thymocytes

I Ogata, T Kawanai, E Hashimoto, Y Nishimura… - Archives of …, 2010 - Springer
German chamomile (Matricaria recutita L.), one of the popular ingredients in herbal teas, has
been traditionally used for medicinal purposes. Bisabololoxide A (BSBO) is one of the main …

Signaling mechanisms and disrupted cytoskeleton in the diphenyl ditelluride neurotoxicity

R Pessoa-Pureur, L Heimfarth… - Oxidative medicine and …, 2014 - Wiley Online Library
Evidence from our group supports that diphenyl ditelluride (PhTe) 2 neurotoxicity depends
on modulation of signaling pathways initiated at the plasma membrane. The (PhTe) 2 …

Cytotoxic action of bisabololoxide A of German chamomile on human leukemia K562 cells in combination with 5-fluorouracil

I Ogata-Ikeda, H Seo, T Kawanai, E Hashimoto… - Phytomedicine, 2011 - Elsevier
German chamomile (Matricaria recutita L.) is a popular ingredient in herbal teas. In previous
study, micromolar bisabololoxide A, one of main constituents in German chamomile, exerted …

Apoptosis-inducing action of two products from oxidation of sesamol, an antioxidative constituent of sesame oil: a possible cytotoxicity of oxidized antioxidant

A Fujimoto, Y Shingai, TB Oyama, T Kawanai… - Toxicology in Vitro, 2010 - Elsevier
Many effects of sesamol, an antioxidative constituent of sesame oil, have been reported for
human health benefits due to its antioxidative action. However, we recently isolated two …

Screening of potentially toxic chalcogens in erythrocytes

VPP Schiar, DB Dos Santos, DS Lüdtke, F Vargas… - Toxicology in vitro, 2007 - Elsevier
Previous literature reports have demonstrated that a number of human diseases, including
inflammation and cancer, can be caused by environmental and occupational exposure to …

Diphenyl ditelluride targets brain selenoproteins in vivo: inhibition of cerebral thioredoxin reductase and glutathione peroxidase in mice after acute exposure

B Comparsi, DF Meinerz, JL Franco, T Posser… - Molecular and Cellular …, 2012 - Springer
In this study, we investigated the effect of diphenyl ditelluride (PhTe) 2 administration (10
and 50 μmol/kg) on adult mouse behavioral performance as well as several parameters of …