Lysine acetylation goes global: from epigenetics to metabolism and therapeutics
Post-translational acetylation of lysine residues has emerged as a key regulatory
mechanism in all eukaryotic organisms. Originally discovered in 1963 as a unique …
mechanism in all eukaryotic organisms. Originally discovered in 1963 as a unique …
[HTML][HTML] Post-translational protein acetylation: an elegant mechanism for bacteria to dynamically regulate metabolic functions
Post-translational modifications (PTM) decorate proteins to provide functional heterogeneity
to an existing proteome. The large number of known PTMs highlights the many ways that …
to an existing proteome. The large number of known PTMs highlights the many ways that …
Feedback control of two-component regulatory systems
EA Groisman - Annual review of microbiology, 2016 - annualreviews.org
Two-component systems are a dominant form of bacterial signal transduction. The
prototypical two-component system consists of a sensor that responds to a specific input (s) …
prototypical two-component system consists of a sensor that responds to a specific input (s) …
Metabolic remodeling during biofilm development of Bacillus subtilis
T Pisithkul, JW Schroeder, EA Trujillo, P Yeesin… - MBio, 2019 - Am Soc Microbiol
Biofilms are structured communities of tightly associated cells that constitute the
predominant state of bacterial growth in natural and human-made environments. Although …
predominant state of bacterial growth in natural and human-made environments. Although …
Bacillus subtilis, the model Gram‐positive bacterium: 20 years of annotation refinement
Genome annotation is, nowadays, performed via automatic pipelines that cannot
discriminate between right and wrong annotations. Given their importance in increasing the …
discriminate between right and wrong annotations. Given their importance in increasing the …
Regulation, function, and detection of protein acetylation in bacteria
VJ Carabetta, IM Cristea - Journal of bacteriology, 2017 - Am Soc Microbiol
ABSTRACT N ε-Lysine acetylation is now recognized as an abundant posttranslational
modification (PTM) that influences many essential biological pathways. Advancements in …
modification (PTM) that influences many essential biological pathways. Advancements in …
Systematic exploration of biotransformation reactions of amine-containing micropollutants in activated sludge
R Gulde, U Meier, EL Schymanski… - … science & technology, 2016 - ACS Publications
The main removal process for polar organic micropollutants during activated sludge
treatment is biotransformation, which often leads to the formation of stable transformation …
treatment is biotransformation, which often leads to the formation of stable transformation …
Mechanisms, detection, and relevance of protein acetylation in prokaryotes
DG Christensen, JT Baumgartner, X Xie, KM Jew… - MBio, 2019 - Am Soc Microbiol
Posttranslational modification of a protein, either alone or in combination with other
modifications, can control properties of that protein, such as enzymatic activity, localization …
modifications, can control properties of that protein, such as enzymatic activity, localization …
[HTML][HTML] Psychosocial stress and cortisol stress reactivity predict breast milk composition
A Ziomkiewicz, M Babiszewska, A Apanasewicz… - Scientific reports, 2021 - nature.com
We studied a sample of 146 Polish, exclusively breastfeeding mothers and their healthy
born on time infants to explore the effect of perinatal psychosocial stress on breast milk …
born on time infants to explore the effect of perinatal psychosocial stress on breast milk …
[HTML][HTML] Acetylation of Lysine 201 Inhibits the DNA-Binding Ability of PhoP to Regulate Salmonella Virulence
J Ren, Y Sang, Y Tan, J Tao, J Ni, S Liu, X Fan… - PLoS …, 2016 - journals.plos.org
The two-component system PhoP-PhoQ is highly conserved in bacteria and regulates
virulence in response to various signals for bacteria within the mammalian host. Here, we …
virulence in response to various signals for bacteria within the mammalian host. Here, we …