Chronic wounds

V Falanga, RR Isseroff, AM Soulika… - Nature Reviews …, 2022 - nature.com
Chronic wounds are characterized by their inability to heal within an expected time frame
and have emerged as an increasingly important clinical problem over the past several …

Microbiota and maintenance of skin barrier function

TA Harris-Tryon, EA Grice - Science, 2022 - science.org
Human skin forms a protective barrier against the external environment and is our first line of
defense against toxic, solar, and pathogenic insults. Our skin also defines our outward …

Biomaterials releasing drug responsively to promote wound healing via regulation of pathological microenvironment

H Li, B Li, D Lv, W Li, Y Lu, G Luo - Advanced Drug Delivery Reviews, 2023 - Elsevier
Wound healing is characterized by complex, orchestrated, spatiotemporal dynamic
processes. Recent findings demonstrated suitable local microenvironments were …

Why traditional herbal medicine promotes wound healing: Research from immune response, wound microbiome to controlled delivery

Z Xu, M Dong, S Yin, J Dong, M Zhang, R Tian… - Advanced Drug Delivery …, 2023 - Elsevier
Impaired wound healing in chronic wounds has been a significant challenge for clinicians
and researchers for decades. Traditional herbal medicine (THM) has a long history of …

Exploring the Role of Staphylococcus aureus in Inflammatory Diseases

H Chen, J Zhang, Y He, Z Lv, Z Liang, J Chen, P Li… - Toxins, 2022 - mdpi.com
Staphylococcus aureus is a very common Gram-positive bacterium, and S. aureus infections
play an extremely important role in a variety of diseases. This paper describes the types of …

Wound healing and microbiome, an unexpected relationship

L Canchy, D Kerob, AL Demessant… - Journal of the …, 2023 - Wiley Online Library
Skin wounds are common and represent a major public health and economical problem,
with risks of complications and a significant negative impact on the quality of life of patients …

The skin microbiome: current landscape and future opportunities

P Smythe, HN Wilkinson - International journal of molecular sciences, 2023 - mdpi.com
Our skin is the largest organ of the body, serving as an important barrier against the harsh
extrinsic environment. Alongside preventing desiccation, chemical damage and …

Building and maintaining the skin

YC Hsu, E Fuchs - Cold Spring Harbor perspectives in …, 2022 - cshperspectives.cshlp.org
The skin forms a crucial, dynamic barrier between an animal and the external world. In
mammals, three stem cell populations possess robust regenerative potential to maintain and …

Role of wound microbiome, strategies of microbiota delivery system and clinical management

Q Tang, N Xue, X Ding, KHY Tsai, JJ Hew… - Advanced Drug Delivery …, 2023 - Elsevier
Delayed wound healing is one of the most global public health threats affecting nearly 100
million people each year, particularly the chronic wounds. Many confounding factors such as …

The wound microbiota: microbial mechanisms of impaired wound healing and infection

A Uberoi, A McCready-Vangi, EA Grice - Nature Reviews Microbiology, 2024 - nature.com
The skin barrier protects the human body from invasion by exogenous and pathogenic
microorganisms. A breach in this barrier exposes the underlying tissue to microbial …