Purpose The chemokine receptor CXCR4 is a promising target for molecular imaging of
CXCR4+ cell types, eg inflammatory cells, in cardiovascular diseases. We speculated that a …

CXC motif chemokine receptor 4 (CXCR4) is expressed on the surface of various cell types
involved in atherosclerosis, with a particularly rich receptor expression on macrophages and …

Purpose Small molecules targeting fibroblast activation protein (FAP) have emerged as a
new group of tracers for positron emission tomography (PET) in 2018. While most of the …

Background Idiopathic pulmonary fibrosis (IPF) is a progressive disease for which two
antifibrotic drugs recently were approved. However, an unmet need exists to predict …

Cardiovascular diseases (CVDs) have been the leading cause of death in United States.
While tremendous progress has been made for treating CVDs over the year, the high …

Abstract Purpose of Review Successful treatment of cancer can be hampered by the
attendant risk of cardiotoxicity, manifesting as cardiomyopathy, left ventricle systolic …

Despite decades of research, the heart-brain axis continues to challenge investigators
seeking to unravel its complex pathobiology. Strong epidemiologic evidence supports a link …

CXC-motif chemokine receptor 4 (CXCR4) is a novel predictive biomarker for metastasis
and poor prognosis in individuals with malignancies. CXCL12 is the only cognate ligand of …

CXC motif chemokine receptor 4 (CXCR4) is an attractive target for cancer diagnosis and
treatment, as it is overexpressed in many solid and hematologic malignancies. This study …

Fluorine-19 (19F) magnetic resonance imaging is a unique quantitative molecular imaging
modality that makes use of an injectable fluorine-containing tracer that generates the only …