pH-Responsive polymers: synthesis, properties and applications

S Dai, P Ravi, KC Tam - Soft Matter, 2008 - pubs.rsc.org
pH-Responsive polymers are systems whose solubility, volume, and chain conformation can
be manipulated by changes in pH, co-solvent, and electrolytes. This review summarizes …

Nanopreparations to overcome multidrug resistance in cancer

NR Patel, BS Pattni, AH Abouzeid… - Advanced drug delivery …, 2013 - Elsevier
Multidrug resistance is the most widely exploited phenomenon by which cancer eludes
chemotherapy. Broad variety of factors, ranging from the cellular ones, such as over …

Poly-ε-caprolactone (PCL), a promising polymer for pharmaceutical and biomedical applications: Focus on nanomedicine in cancer

SM Espinoza, HI Patil, ESM Martinez… - … Journal of Polymeric …, 2019 - Taylor & Francis
Abstract Poly-ε-caprolactone (PCL) has been the subject of extensive research in the past
few years. It is widely explored in drug delivery, where the development of nanomedicines …

Soluble single-walled carbon nanotubes as longboat delivery systems for platinum (IV) anticancer drug design

RP Feazell, N Nakayama-Ratchford… - Journal of the …, 2007 - ACS Publications
Amine-functionalized soluble single-walled carbon nanotubes (SWNTs) were derivatized
with cisplatin prodrug conjugates as a delivery system by which to internalize multiple …

Polymer− cisplatin conjugate nanoparticles for acid-responsive drug delivery

S Aryal, CMJ Hu, L Zhang - ACS nano, 2010 - ACS Publications
We report the synthesis of novel acid-responsive therapeutic nanoparticles (NPs) with sub-
100 nm size consisting of polymer− cisplatin conjugates. The uniqueness of these drug …

Porous Hollow Fe3O4 Nanoparticles for Targeted Delivery and Controlled Release of Cisplatin

K Cheng, S Peng, C Xu, S Sun - Journal of the American Chemical …, 2009 - ACS Publications
We report a new approach to cisplatin storage and release using porous hollow
nanoparticles (PHNPs) of Fe3O4. We prepared the PHNPs by controlled oxidation of Fe NPs …

Nanoparticle formulations of cisplatin for cancer therapy

X Duan, C He, SJ Kron, W Lin - Wiley Interdisciplinary Reviews …, 2016 - Wiley Online Library
The genotoxic agent cisplatin, used alone or in combination with radiation and/or other
chemotherapeutic agents, is an important first‐line chemotherapy for a broad range of …

Tumoral acidic pH-responsive MPEG-poly (β-amino ester) polymeric micelles for cancer targeting therapy

KH Min, JH Kim, SM Bae, H Shin, MS Kim… - Journal of Controlled …, 2010 - Elsevier
Herein, we evaluated the tumoral low pH targeting characteristics of pH-responsive polymer
micelles in cancer targeting therapy. To design the pH-responsive polymeric micelles …

Release mechanisms for polyelectrolyte capsules

BG De Geest, NN Sanders, GB Sukhorukov… - Chemical Society …, 2007 - pubs.rsc.org
Polyelectrolyte capsules have recently been introduced as new microscopic vehicles which
could have high potential in the biomedical field. In this critical review we give an …

Challenges in design of translational nanocarriers

Q Sun, M Radosz, Y Shen - Journal of controlled release, 2012 - Elsevier
Cancer drug delivery achieving high therapeutic efficacy and low side effects requires a
nanocarrier to tightly retain the drug, efficiently reach the tumor, then quickly enter the tumor …