Trigger responsive polymeric nanocarriers for cancer therapy

S Kaur, C Prasad, B Balakrishnan, R Banerjee - Biomaterials science, 2015 - pubs.rsc.org
Conventional chemotherapy for the treatment of cancer has limited specificity when
administered systemically and is often associated with toxicity issues. Enhanced …

A theranostic micelleplex co-delivering SN-38 and VEGF siRNA for colorectal cancer therapy

SY Lee, CY Yang, CL Peng, MF Wei, KC Chen, CJ Yao… - Biomaterials, 2016 - Elsevier
The development of an efficient colorectal cancer therapy is currently a public health priority.
In the present work, we proposed a multifunctional theranostic micellar drug delivery system …

Platinum on nanodiamond: a promising prodrug conjugated with stealth polyglycerol, targeting peptide and acid‐responsive antitumor drug

L Zhao, YH Xu, H Qin, S Abe, T Akasaka… - Advanced Functional …, 2014 - Wiley Online Library
In the field of nanomedicine, nanoparticles with various functions are required for in vivo
applications such as biomedical imaging and drug delivery. Therefore, chemical …

[HTML][HTML] Atom transfer radical polymerization in inverse miniemulsion: a versatile route toward preparation and functionalization of microgels/nanogels for targeted …

JK Oh, SA Bencherif, K Matyjaszewski - Polymer, 2009 - Elsevier
This short review describes application of atom transfer radical polymerization (ATRP) in
inverse miniemulsion and disulfide–thiol exchange to prepare well-defined biodegradable …

pH-responsive and charge shielded cationic micelle of poly (L-histidine)-block-short branched PEI for acidic cancer treatment

J Hu, S Miura, K Na, YH Bae - Journal of Controlled Release, 2013 - Elsevier
To address cancer cell heterogeneity while endowing tumor specificity, the approach of
charge shielding/deshielding was tested in vitro and in vivo with a paclitaxel loaded cationic …

Polymerization-induced self-assembly generating vesicles with adjustable pH-responsive release performance

XF Xu, CY Pan, WJ Zhang, CY Hong - Macromolecules, 2019 - ACS Publications
Stimuli-responsive polymeric vesicles have attracted great attention in drug delivery due to
their intrinsic hollow structures and “on demand” release of drugs upon environmental …

pH and reduction dual-responsive nanogel cross-linked by quaternization reaction for enhanced cellular internalization and intracellular drug delivery

M Li, Z Tang, H Sun, J Ding, W Song, X Chen - Polymer Chemistry, 2013 - pubs.rsc.org
A novel pH and reduction dual-responsive nanogel with improved cellular internalization
was prepared through atom transfer radical polymerization and subsequent quaternization …

Function of gold nanoparticles in oral cancer beyond drug delivery: implications in cell apoptosis

MM Essawy, SM El‐Sheikh, HS Raslan… - Oral …, 2021 - Wiley Online Library
Abstract Objectives Gold nanoparticles (AuNPs) are used to deliver drugs and therapeutic
small molecule inhibitors to cancer cells. Evidence shows that AuNPs coated with nuclear …

The anticancer activity of chloroquine-gold nanoparticles against MCF-7 breast cancer cells

P Joshi, S Chakraborti, JE Ramirez-Vick… - Colloids and Surfaces B …, 2012 - Elsevier
In the present study, 11-mercaptoundecanoic acid-modified gold nanoparticles (∼ 7nm)
were conjugated with chloroquine to explore their potential application in cancer …

Polymers with platinum drugs and other macromolecular metal complexes for cancer treatment

M Callari, JR Aldrich-Wright, PL de Souza… - Progress in Polymer …, 2014 - Elsevier
Metal-based anticancer drugs, in particular platinum-drugs, have been investigated for the
treatment of cancer for the last 40 years. A small set of platinum-based drugs have …