[HTML][HTML] HIV-1 capsid variability: viral exploitation and evasion of capsid-binding molecules
A Saito, M Yamashita - Retrovirology, 2021 - Springer
The HIV-1 capsid, a conical shell encasing viral nucleoprotein complexes, is involved in
multiple post-entry processes during viral replication. Many host factors can directly bind to …
multiple post-entry processes during viral replication. Many host factors can directly bind to …
[HTML][HTML] Toward a macaque model of HIV-1 infection: Roadblocks, progress, and future strategies
The human-specific tropism of Human Immunodeficiency Virus Type 1 (HIV-1) has
complicated the development of a macaque model of HIV-1 infection/AIDS that is suitable for …
complicated the development of a macaque model of HIV-1 infection/AIDS that is suitable for …
Generation of rhesus macaque-tropic HIV-1 clones that are resistant to major anti-HIV-1 restriction factors
M Nomaguchi, M Yokoyama, K Kono… - Journal of …, 2013 - Am Soc Microbiol
Human immunodeficiency virus type 1 (HIV-1) replication in macaque cells is restricted
mainly by antiviral cellular APOBEC3, TRIM5α/TRIM5CypA, and tetherin proteins. For basic …
mainly by antiviral cellular APOBEC3, TRIM5α/TRIM5CypA, and tetherin proteins. For basic …
Chronic hepatitis B and C co-infection increased all-cause mortality in HAART-naive HIV patients in northern Thailand
N Tsuchiya, P Pathipvanich, A Rojanawiwat… - Epidemiology & …, 2013 - cambridge.org
A total of 755 highly active antiretroviral therapy (HAART)-naive HIV-infected patients were
enrolled at a government hospital in Thailand from 1 June 2000 to 15 October 2002. Census …
enrolled at a government hospital in Thailand from 1 June 2000 to 15 October 2002. Census …
[HTML][HTML] Impact of TRIM5α in vivo
EE Nakayama, T Shioda - Aids, 2015 - journals.lww.com
Abstract HIV type 1 (HIV-1) has a very narrow host range that is limited to humans and
chimpanzees. HIV-1 cannot replicate well in Old World monkey cells such as rhesus and …
chimpanzees. HIV-1 cannot replicate well in Old World monkey cells such as rhesus and …
[HTML][HTML] Gain-of-sensitivity mutations in a Trim5-resistant primary isolate of pathogenic SIV identify two independent conserved determinants of Trim5α specificity
KR McCarthy, AG Schmidt, A Kirmaier… - PLoS …, 2013 - journals.plos.org
Retroviral capsid recognition by Trim5 blocks productive infection. Rhesus macaques harbor
three functionally distinct Trim5 alleles: Trim5αQ, Trim5αTFP and Trim5CypA. Despite the …
three functionally distinct Trim5 alleles: Trim5αQ, Trim5αTFP and Trim5CypA. Despite the …
Allosteric regulation of HIV-1 capsid structure for Gag assembly, virion production, and viral infectivity by a disordered interdomain linker
T Koma, O Kotani, K Miyakawa, A Ryo… - Journal of …, 2019 - Am Soc Microbiol
ABSTRACT The retroviral Gag capsid (Gag-CA) interdomain linker is an unstructured
peptide segment connecting structured N-terminal and C-terminal domains. Although the …
peptide segment connecting structured N-terminal and C-terminal domains. Although the …
[HTML][HTML] Grand challenge in human/animal virology: unseen, smallest replicative entities shape the whole globe
A Adachi - Frontiers in Microbiology, 2020 - frontiersin.org
By far the most abundant species in nature is the virus that cannot replicate by itself. Viruses,
parasitic entities, are found in virtually all unicellular and multicellular creatures. Viruses are …
parasitic entities, are found in virtually all unicellular and multicellular creatures. Viruses are …
[PDF][PDF] 平顶猴在HIV/AIDS 动物模型中的应用及研究进展
雷爱华， 庞伟， 张高红， 郑永唐 - 动物学研究, 2013 - pdfs.semanticscholar.org
非人灵长类动物模型在HIV-1 致病机制研究以及抗AIDS 药物和疫苗研发中具有重要作用.
由于缺乏HIV-1 直接感染的动物, SIV/SHIV 猕猴模型是目前AIDS 研究中应用最为广泛的动物 …
由于缺乏HIV-1 直接感染的动物, SIV/SHIV 猕猴模型是目前AIDS 研究中应用最为广泛的动物 …
[HTML][HTML] Systemic biological analysis of the mutations in two distinct HIV-1mt genomes occurred during replication in macaque cells
Fundamental property of viruses is to rapidly adapt themselves under changing conditions of
virus replication. Using HIV-1 derivatives that poorly replicate in macaque cells as model …
virus replication. Using HIV-1 derivatives that poorly replicate in macaque cells as model …