Adverse effects of low dose amiodarone: a meta-analysis

VR Vorperian, TC Havighurst, S Miller… - Journal of the American …, 1997 - jacc.org
Objectives. We sought to assess the odds of experiencing adverse effects with low dose
amiodarone therapy compared with placebo. Background. An estimate of the likelihood of …

Cellular electropharmacology of amiodarone

I Kodama, K Kamiya, J Toyama - Cardiovascular research, 1997 - academic.oup.com
Antiarrhythmic strategies have changed dramatically during the last decade. The Cardiac
Arrhythmia Suppres-Ž. sion Trial CAST reported the harmful effects of flecainide, encainide …

Atrial fibrillation in hypertrophie cardiomyopathy: a longitudinal study

K Robinson, MP Frenneaux, B Stockins… - Journal of the American …, 1990 - Elsevier
The clinical outcome of 52 consecutive patients with hypertrophic cardiomyopathy who
developed paroxysmal (< 1 week) or established (≥ l week) atrial fibrillation between 1960 …

Effect of antiarrhythmic therapy on mortality in survivors of myocardial infarction with asymptomatic complex ventricular arrhythmias: Basel Antiarrhythmic Study of …

F Burkart, M Pfisterer, W Kiowski, F Follath… - Journal of the American …, 1990 - Elsevier
In view of the high risk of sudden cardiac death and the prognostic importance of complex
ventricular ectopic activity, the effects of prophylactic antiarrhythmic treatment were …

Amiodarone: electrophysiologic actions, pharmacokinetics and clinical effects

DP Zipes, EN Prystowsky, JJ Heger - Journal of the American College of …, 1984 - Elsevier
Interest in amiodarone has increased because of its remarkable efficacy as an
antiarrhythmic agent. The purpose of this report is to review what is known about the …

Amiodarone: reevaluation of an old drug

PJ Podrid - Annals of internal medicine, 1995 - acpjournals.org
Purpose: To review the pharmacology, electrophysiology, and toxicity of amiodarone and to
discuss the clinical results produced when amiodarone is used as therapy for patients with …

Steady-state serum amiodarone concentrations: relationships with antiarrhythmic efficacy and toxicity

HH ROTMENSCH, B BELHASSEN… - Annals of internal …, 1984 - acpjournals.org
The relationship of apparent steady-state serum concentrations of amiodarone and its
metabolite, desethylamiodarone, to therapeutic and toxic effects was assessed in 127 …

Amiodarone for refractory atrial fibrillation

RL Gold, CI Haffajee, G Charos, K Sloan… - The American journal of …, 1986 - Elsevier
Atrial fibrilation (AF) is a difficult arrhythmia to manage with antiarrhythmic agents.
Amiodarone is highly effective in restoring and maintaining normal sinus rhythm in patients …

Pharmacology and pharmacokinetics of amiodarone.

MD Freedman, JC Somberg - Journal of clinical pharmacology, 1991 - europepmc.org
Amiodarone is a unique antiarrhythmic agent originally developed as a vasodilator.
Classified electrophysiologically as a Type III antiarrhythmic, it also has both nonspecific …

Amiodarone pulmonary toxicity: CT findings in symptomatic patients.

JE Kuhlman, C Teigen, H Ren, RH Hruban… - Radiology, 1990 - pubs.rsna.org
The computed tomographic (CT) chest scans of 11 patients who developed respiratory or
constitutional symptoms while receiving amiodarone therapy were reviewed. CT findings …