Visualizing and perturbing neural activity on a brain-wide scale in model animals and
humans is a major goal of neuroscience technology development. Established electrical and …

Ultrasound sensitivity to slow blood flow motion gained two orders of magnitude in the last
decade thanks to the advent of ultrafast ultrasound imaging at thousands of frames per …

Functional ultrasound (fUS) is a neuroimaging method that uses ultrasound to track changes
in cerebral blood volume as an indirect readout of neuronal activity at high spatiotemporal …

Focused ultrasound (FUS) neuromodulation has shown that mechanical waves can interact
with cell membranes and mechanosensitive ion channels, causing changes in neuronal …

Background and Purpose Oncological neurosurgery relies heavily on making continuous,
intra-operative tumor-brain delineations based on image-guidance. Limitations of currently …

New technologies are key to understanding the dynamic activity of neural circuits and
systems in the brain. Here, we show that a minimally invasive approach based on …

Most brain functions engage a network of distributed regions. Full investigation of these
functions thus requires assessment of whole brains; however, whole-brain functional …

Functional ultrasound imaging (fUS) is an emerging technique that detects changes of
cerebral blood volume triggered by brain activation. Here, we investigate the extent to which …

Deep regions of the brain are not easily accessible to investigation at the mesoscale level in
awake animals or humans. We have recently developed a functional ultrasound (fUS) …

For beamforming ultrasound (US) signals, typically a spatially constant speed-of-sound
(SoS) is assumed to calculate delays. As SoS in tissue may vary relatively largely, this …