Influenza is an acute viral respiratory infection that affects all age groups and is associated
with high mortality during pandemics, epidemics, and sporadic outbreaks. Nearly 10% of the …

The influenza A virus infection continues to be a threat to the human population. The
seasonal variation of the virus and the likelihood of periodical pandemics caused by …

Influenza virus remains a threat because of its ability to evade vaccine-induced immune
responses due to antigenic drift. Here, we describe the isolation, evolution, and structure of a …

Highlights•Broadly neutralizing antibodies against influenza A and B represents a safe and
affordable alternative to convalescent plasma.•The large majority of broadly neutralizing …

The avian influenza A virus (AIV) is naturally prevalent in aquatic birds, infecting different
avian species and transmitting from birds to humans. Both AIVs, the H5N1 and H7N9 …

There is an unmet public health need for a universal influenza vaccine (UIV) to provide
broad and durable protection from influenza virus infections. The identification of broadly …

Due to limitations of current influenza virus vaccines, new vaccines that mediate broad
protection and show high efficacy against seasonal and pandemic viruses are urgently …

Improved broad-spectrum influenza virus vaccines are desperately needed to provide
protection against both drifted seasonal and emerging pandemic influenza A viruses (IAVs) …

It is evident that the emergence of infectious diseases, which have the potential for spillover
from animal reservoirs, pose an ongoing threat to global health. Zoonotic transmission …

Since the development of the first vaccine against smallpox over two centuries ago,
vaccination strategies have been at the forefront of significantly impacting the incidences of …