Nature gives immense resources that are beneficial to humankind. The natural compounds
present in plants provide primary nutritional values to our diet. Apart from food, plants also …

Background Liver is a vital organ responsible for metabolizing and detoxifying both
endogenous and exogenous substances in the body. However, it is susceptible to damage …

Hepatotoxicity caused by chemotherapeutic drugs (eg, doxorubicin) is of critical concern in
cancer therapy. This study focused on investigating the modulatory effects of diosmin …

There are numerous prescription drugs and non-prescription drugs that cause drug-induced
liver injury (DILI), which is the main cause of liver disease in humans around the globe. Its …

Flavonoids have been shown to have anti-oxidative effects, as well as other health benefits
(eg, anti-inflammatory and anti-tumor functions). Luteolin (3′, 4′, 5, 7-tetrahydroxyflavone) …

Sorghum bicolor plant has a high abundance of 3-deoxyanthocyanins, flavonoids and other
polyphenol compounds that have been shown to offer numerous health benefits …

Cancer is one of the leading causes of death worldwide, so pursuing effective and safe
therapeutics for cancer is a key research objective nowadays. Doxorubicin (DOX) is one of …

Human colon microbiota produce a metabolite called urolithin A (URO A) from ellagic acid
and linked compounds, and this metabolite has been demonstrated to have antioxidant, anti …

Acute kidney injury (AKI) has been increasingly reported in critically-ill COVID-19 patients.
Moreover, there was significant positive correlation between COVID-19 deaths and renal …

Doxorubicin-mediated kidney impairment is a serious problem in cancer treatment.
Accordingly, this work investigated the ability of geraniol to modulate doxorubicin-induced …