The prevalence of cardiovascular disease (CVD) is increasing over time. CVD is a
comorbidity in diabetes and contributes to premature death. Citrus flavonoids possess …

Inflammation and oxidative stress are two major causes of various life‐threatening diseases.
Hesperidin (Hsd) and its aglycone, hesperetin (Hst), are two flavonoids from citrus species …

The dietary flavonoids, especially their glycosides, are the most vital phytochemicals in diets
and are of great general interest due to their diverse bioactivity. The natural flavonoids …

Dysregulation of circadian rhythms is associated with metabolic dysfunction, yet it is unclear
whether enhancing clock function can ameliorate metabolic disorders. In an unbiased …

Recently, hesperidin, a flavonone mainly present in citrus fruits, has emerged as a new
potential therapeutic agent able to modulate several cardiovascular diseases (CVDs) risk …

Abstract Ethnopharmacological relevance Citri Reticulatae Pericarpium (Rutaceae, CRP),
commonly called as Chenpi (陈皮) in Chinese, is most frequently used as a qi-regulating …

Type 2 diabetes mellitus (T2DM) is a metabolic disease characterized by insulin resistance
and hyperglycemia and is associated with personal health and global economic burdens …

Polyphenols are an important class of phytochemicals, and several lines of evidence have
demonstrated their beneficial effects in the context of a number of pathologies including …

Obesity and its associated diseases such as diabetes mellitus and coronary heart diseases
are a major challenge for our society. An important target for the treatment of obesity …

Obesity is a chronic metabolic disease caused by multiple factors and is considered to be a
risk factor for type 2 diabetes, cardiovascular disease, hypertension, stroke and various …