Adoptive T‐cell therapy targeting Epstein–Barr virus as a treatment for multiple sclerosis

C Smith, R Khanna - Clinical & translational immunology, 2023 - Wiley Online Library
Emergence of a definitive link between Epstein–Barr virus (EBV) and multiple sclerosis has
provided an impetus to develop immune‐based therapies to target EBV‐infected B cells …

[HTML][HTML] Risk factors for multiple sclerosis in the context of Epstein-Barr virus infection

AK Hedström - Frontiers in Immunology, 2023 - frontiersin.org
Compelling evidence indicates that Epstein Barr virus (EBV) infection is a prerequisite for
multiple sclerosis (MS). The disease may arise from a complex interplay between latent EBV …

The potential for EBV vaccines to prevent multiple sclerosis

PA Maple, A Ascherio, JI Cohen, G Cutter… - Frontiers in …, 2022 - frontiersin.org
There is increasing evidence suggesting that Epstein-Barr virus infection is a causative
factor of multiple sclerosis (MS). Epstein-Barr virus (EBV) is a human herpesvirus, Human …

Vitamin D did not reduce multiple sclerosis disease activity after a clinically isolated syndrome

H Butzkueven, AL Ponsonby, MS Stein, RM Lucas… - Brain, 2024 - academic.oup.com
Low serum levels of 25-hydroxyvitamin D [25 (OH) D] and low sunlight exposure are known
risk factors for the development of multiple sclerosis. Add-on vitamin D supplementation …

[HTML][HTML] Multiple sclerosis: therapeutic strategies on the horizon

RT Manjunatha, S Habib, SL Sangaraju, D Yepez… - Cureus, 2022 - ncbi.nlm.nih.gov
Multiple sclerosis (MS) is a chronic disease affecting the brain and the spinal cord. It is a
chronic inflammatory demyelinating disease of the central nervous system. It is the leading …

[HTML][HTML] Effects of Environmental Factors and Epigenetic on Health and the Development of Diseases

M Farrokhi, F Taheri, E Karami, R Khorram… - Kindle, 2023 - preferpub.org
The effects of environmental factors and epigenetics on health and disease development
are complex and interconnected. Environmental factors encompass external influences like …

Global burden of vaccine‐associated multiple sclerosis, 1967–2022: A comprehensive analysis of the international pharmacovigilance database

HG Woo, HJ Kim, J Park, J Lee, H Lee… - Journal of Medical …, 2024 - Wiley Online Library
Vaccine‐associated multiple sclerosis (MS) is rare, with insufficient evidence from case
reports. Given the scarcity of large‐scale data investigating the association between vaccine …

[HTML][HTML] Advantages and limitations of experimental autoimmune encephalomyelitis in breaking down the role of the gut microbiome in multiple sclerosis

E Melamed, JL Palmer, C Fonken - Frontiers in Molecular …, 2022 - frontiersin.org
Since the first model of experimental autoimmune encephalomyelitis (EAE) was introduced
almost a century ago, there has been an ongoing scientific debate about the risks and …

Increasing incidence and prevalence of multiple sclerosis in the Greater Hobart cohort of Tasmania, Australia

S Simpson-Yap, R Atvars, L Blizzard… - Journal of Neurology …, 2022 - jnnp.bmj.com
Background The Greater Hobart region (42.5° S) of Tasmania has consistently had the
highest recorded prevalence and incidence rates of multiple sclerosis (MS) in Australia. We …

Ensemble machine learning identifies genetic loci associated with future worsening of disability in people with multiple sclerosis

V Fuh-Ngwa, Y Zhou, PE Melton, I van der Mei… - Scientific Reports, 2022 - nature.com
Limited studies have been conducted to identify and validate multiple sclerosis (MS) genetic
loci associated with disability progression. We aimed to identify MS genetic loci associated …