[HTML][HTML] Targeting endothelial cells with golden spice curcumin: A promising therapy for cardiometabolic multimorbidity

F Tang, D Liu, L Zhang, LY Xu, JN Zhang… - Pharmacological …, 2023 - Elsevier
Cardiometabolic multimorbidity (CMM) is an increasingly significant global public health
concern. It encompasses the coexistence of multiple cardiometabolic diseases, including …

[HTML][HTML] The role of cellular crosstalk in the progression of diabetic nephropathy

K Zhang, Z Fu, Y Zhang, X Chen, G Cai… - Frontiers in …, 2023 - frontiersin.org
Diabetic nephropathy (DN) is one of the most common complications of diabetes, and its
main manifestations are progressive proteinuria and abnormal renal function, which …

[HTML][HTML] Klotho's impact on diabetic nephropathy and its emerging connection to diabetic retinopathy

A Tang, Y Zhang, L Wu, Y Lin, L Lv, L Zhao… - Frontiers in …, 2023 - frontiersin.org
Diabetic nephropathy (DN) is the leading cause of end-stage renal disease worldwide and
is a significant burden on healthcare systems. α-klotho (klotho) is a protein known for its anti …

[HTML][HTML] Exploring the impact of glycemic control on diabetic retinopathy: emerging models and prognostic implications

N Tecce, G Cennamo, M Rinaldi, C Costagliola… - Journal of Clinical …, 2024 - mdpi.com
This review addresses the complexities of type 1 diabetes (T1D) and its associated
complications, with a particular focus on diabetic retinopathy (DR). This review outlines the …

Piezo1 mediates vasodilation induced by acute hyperglycemia in mouse renal arteries and microvessels

L Fei, M Xu, H Wang, C Zhong, S Jiang… - …, 2023 - Am Heart Assoc
BACKGROUND: Acute hyperglycemia is a risk factor for developing acute kidney injury and
poor renal outcome in critically ill patients, whereby the role of renal vasculature remains …

The mechanism of EGFL7 regulating neovascularization in diabetic retinopathy through the PI3K/AKT/VEGFA pathway

Y Xian, XL Wang, Y Yu, XL Chen - Life Sciences, 2024 - Elsevier
Diabetic retinopathy (DR) is a blinding disease caused by diabetes, characterized by
neovascularization of the retina. The aim of this study was to investigate the roles of …

Syringaresinol Alleviates Early Diabetic Retinopathy by Downregulating HIF‐1α/VEGF via Activating Nrf2 Antioxidant Pathway

C Liu, T Cheng, Y Wang, G Li, Y Wang… - Molecular Nutrition & …, 2024 - Wiley Online Library
Scope Early diabetic retinopathy (DR) is characterized by chronic inflammation, excessive
oxidative stress, and retinal microvascular damage. Syringaresinol (SYR), as a natural …

[HTML][HTML] Circular RNAs: An emerging precise weapon for diabetic nephropathy diagnosis and therapy

H Shu, Z Zhang, J Liu, P Chen, C Yang, Y Wu… - Biomedicine & …, 2023 - Elsevier
Diabetic nephropathy (DN) is a prevalent chronic microvascular complication associated
with diabetes mellitus and represents a major cause of chronic kidney disease and renal …

[HTML][HTML] Mechanism of traditional Chinese medicine in elderly diabetes mellitus and a systematic review of its clinical application

Q Zhang, S Hu, Z Jin, S Wang, B Zhang… - Frontiers in …, 2024 - frontiersin.org
Objective: Affected by aging, the elderly diabetes patients have many pathological
characteristics different from the young people, including more complications, vascular …

Jin-Gui-Shen-Qi Wan alleviates fibrosis in mouse diabetic nephropathy via MHC class II

D Liang, L Liu, Y Qi, F Nan, J Huang, S Tang… - Journal of …, 2024 - Elsevier
Abstract Ethnopharmacological relevance Jin-Gui-Shen-Qi Wan (JGSQW) is a traditional
Chinese medicine formula that has been traditionally used to alleviate urinary system …