The global ascendency of OXA-48-type carbapenemases

JDD Pitout, G Peirano, MM Kock… - Clinical microbiology …, 2019 - Am Soc Microbiol
Surveillance studies have shown that OXA-48-like carbapenemases are the most common
carbapenemases in Enterobacterales in certain regions of the world and are being …

Aetiology of invasive bacterial infection and antimicrobial resistance in neonates in sub-Saharan Africa: a systematic review and meta-analysis in line with the …

U Okomo, ENK Akpalu, K Le Doare, A Roca… - The Lancet Infectious …, 2019 - thelancet.com
Background Aetiological data for neonatal infections are essential to inform policies and
programme strategies, but such data are scarce from sub-Saharan Africa. We therefore …

Antimicrobial resistance among children in sub-Saharan Africa

PCM Williams, D Isaacs, JA Berkley - The Lancet Infectious Diseases, 2018 - thelancet.com
Antimicrobial resistance is an important threat to international health. Therapeutic guidelines
for empirical treatment of common life-threatening infections depend on available …

Dynamics of antimicrobial resistance in intestinal Escherichia coli from children in community settings in South Asia and sub-Saharan Africa

DJ Ingle, MM Levine, KL Kotloff, KE Holt… - Nature …, 2018 - nature.com
The dynamics of antimicrobial resistance (AMR) in developing countries are poorly
understood, especially in community settings, due to a sparsity of data on AMR prevalence …

[HTML][HTML] Outbreak of NDM-1–and OXA-181–producing klebsiella pneumoniae bloodstream infections in a neonatal unit, South Africa

RE Magobo, H Ismail, M Lowe… - Emerging Infectious …, 2023 - ncbi.nlm.nih.gov
After an increase in carbapenem-resistant Klebsiella pneumoniae (CRKP) bloodstream
infections and associated deaths in the neonatal unit of a South Africa hospital, we …

Novel chromosomal insertions of IS Ecp1-bla CTX-M-15 and diverse antimicrobial resistance genes in Zambian clinical isolates of Enterobacter cloacae and …

M Shawa, Y Furuta, G Mulenga, M Mubanga… - … Resistance & Infection …, 2021 - Springer
Background The epidemiology of extended-spectrum β-lactamases (ESBLs) has undergone
dramatic changes, with CTX-M-type enzymes prevailing over other types. bla CTX-M genes …

Spread of plasmid-encoded NDM-1 and GES-5 carbapenemases among extensively drug-resistant and pandrug-resistant clinical Enterobacteriaceae in Durban …

T Pedersen, JO Sekyere, U Govinden… - Antimicrobial agents …, 2018 - Am Soc Microbiol
Whole-genome sequence analyses revealed the presence of bla NDM-1 (n= 31), bla GES-5
(n= 8), bla OXA-232 (n= 1), or bla NDM-5 (n= 1) in extensively drug-resistant and pandrug …

Epidemiology and prevalence of extended-spectrum β-lactamase-and carbapenemase-producing Enterobacteriaceae in humans, animals and the environment in …

OO Mahamat, M Kempf, M Lounnas, A Tidjani… - International journal of …, 2021 - Elsevier
Extended-spectrum β-lactamase-producing Enterobacteriaceae (ESBL-E) and
carbapenemase-producing Enterobacteriaceae (CPE) are widespread. Here we used the …

Ringing bells: Morganella morganii fights for recognition

A Bandy - Public Health, 2020 - Elsevier
Objectives The global increase in rare opportunistic microbial infections is alarming. The
current review was undertaken to study the diversified disease spectrum, pathogenicity, and …

Review and analysis of the overlapping threats of carbapenem and polymyxin resistant E. coli and Klebsiella in Africa

DM Venne, DM Hartley, MD Malchione, M Koch… - … Resistance & Infection …, 2023 - Springer
Abstract Background Carbapenem-resistant Enterobacterales are among the most serious
antimicrobial resistance (AMR) threats. Emerging resistance to polymyxins raises the …