The treatment of tuberculosis
CA Peloquin, GR Davies - Clinical Pharmacology & …, 2021 - Wiley Online Library
Tuberculosis (TB) remains a leading cause of infectious death worldwide, and poverty is a
major driver. Clinically, TB presents as “latent” TB and active TB disease, and the treatment …
major driver. Clinically, TB presents as “latent” TB and active TB disease, and the treatment …
Toward SERS-based therapeutic drug monitoring in clinical settings: Recent developments and trends
C Liu, S Weber, R Peng, L Wu, W Zhang… - TrAC Trends in …, 2023 - Elsevier
Therapeutic drug monitoring (TDM) plays an important role in ensuring optimal drug therapy
and has become increasingly important in clinical practice. In the first part of this review …
and has become increasingly important in clinical practice. In the first part of this review …
Clinical standards for the dosing and management of TB drugs
JWC Alffenaar, SL Stocker, LD Forsman… - … of Tuberculosis and …, 2022 - ingentaconnect.com
BACKGROUND: Optimal drug dosing is important to ensure adequate response to
treatment, prevent development of drug resistance and reduce drug toxicity. The aim of …
treatment, prevent development of drug resistance and reduce drug toxicity. The aim of …
Therapeutic drug monitoring of antibiotics: defining the therapeutic range
MH Abdul–Aziz, K Brady, MO Cotta… - Therapeutic drug …, 2022 - journals.lww.com
Purpose: In the present narrative review, the authors aimed to discuss the relationship
between the pharmacokinetic/pharmacodynamic (PK/PD) of antibiotics and clinical …
between the pharmacokinetic/pharmacodynamic (PK/PD) of antibiotics and clinical …
[HTML][HTML] New approach to rifampicin stability and first-line anti-tubercular drug pharmacokinetics by UPLC-MS/MS
M Karaźniewicz-Łada, K Kosicka-Noworzyń… - … of Pharmaceutical and …, 2023 - Elsevier
Successful tuberculosis (TB) therapy requires achieving sufficient exposure to multiple
drugs. Limited stability of several first-line anti-TB drugs might compromise reliable …
drugs. Limited stability of several first-line anti-TB drugs might compromise reliable …
The role of surface enhanced Raman scattering for therapeutic drug monitoring of antimicrobial agents
The rapid quantification of antimicrobial agents is important for therapeutic drug monitoring
(TDM), enabling personalized dosing schemes in critically ill patients. Highly sophisticated …
(TDM), enabling personalized dosing schemes in critically ill patients. Highly sophisticated …
Parametric population pharmacokinetics of linezolid: a systematic review
Y Qin, LL Zhang, YR Ye, YT Chen… - British Journal of Clinical …, 2022 - Wiley Online Library
Aims Linezolid is often used for the infections caused by drug‐resistant Gram‐positive
bacteria. Recent studies suggest that large between‐subject variability (BSV) and within …
bacteria. Recent studies suggest that large between‐subject variability (BSV) and within …
Effect of NAT2, GSTM1 and CYP2E1 genetic polymorphisms on plasma concentration of isoniazid and its metabolites in patients with tuberculosis, and the …
V Ulanova, A Kivrane, A Viksna, L Pahirko… - Frontiers in …, 2024 - frontiersin.org
Objectives: Isoniazid is a key drug in the chemotherapy of tuberculosis (TB), however,
interindividual variability in pharmacokinetic parameters and drug plasma levels may affect …
interindividual variability in pharmacokinetic parameters and drug plasma levels may affect …
Clinical standards for drug-susceptible pulmonary TB
OW Akkerman, R Duarte, S Tiberi… - … of Tuberculosis and …, 2022 - ingentaconnect.com
BACKGROUND: The aim of these clinical standards is to provide guidance on 'best practice´
for diagnosis, treatment and management of drug-susceptible pulmonary TB (PTB) …
for diagnosis, treatment and management of drug-susceptible pulmonary TB (PTB) …
Semi-automated therapeutic drug monitoring as a pillar toward personalized medicine for tuberculosis management
Standard tuberculosis (TB) management has failed to control the growing number of drug-
resistant TB cases worldwide. Therefore, innovative approaches are required to eradicate …
resistant TB cases worldwide. Therefore, innovative approaches are required to eradicate …