Oocyte maturation: gamete-somatic cells interactions, meiotic resumption, cytoskeletal dynamics and cytoplasmic reorganization
G Coticchio, M Dal Canto… - Human reproduction …, 2015 - academic.oup.com
BACKGROUND In a growth phase occurring during most of folliculogenesis, the oocyte
produces and accumulates molecules and organelles that are fundamental for the …
produces and accumulates molecules and organelles that are fundamental for the …
Oocyte mitochondrial function and reproduction
Optimal energy production is required for oocyte and embryo development, and
mitochondrial abnormalities have devastating reproductive consequences. Improvement of …
mitochondrial abnormalities have devastating reproductive consequences. Improvement of …
Maternal metabolic syndrome programs mitochondrial dysfunction via germline changes across three generations
JL Saben, AL Boudoures, Z Asghar, A Thompson… - Cell reports, 2016 - cell.com
Maternal obesity impairs offspring health, but the responsible mechanisms are not fully
established. To address this question, we fed female mice a high-fat/high-sugar diet from …
established. To address this question, we fed female mice a high-fat/high-sugar diet from …
Oocyte mitochondria—Key regulators of oocyte function and potential therapeutic targets for improving fertility
The development of oocytes and early embryos is dependent on mitochondrial ATP
production. This reliance on mitochondrial activity, together with the exclusively maternal …
production. This reliance on mitochondrial activity, together with the exclusively maternal …
Mitofusins: from mitochondria to fertility
S Zhao, N Heng, H Wang, H Wang, H Zhang… - Cellular and Molecular …, 2022 - Springer
Germ cell formation and embryonic development require ATP synthesized by mitochondria.
The dynamic system of the mitochondria, and in particular, the fusion of mitochondria, are …
The dynamic system of the mitochondria, and in particular, the fusion of mitochondria, are …
Mitochondrial GTP metabolism controls reproductive aging in C. elegans
Healthy mitochondria are critical for reproduction. During aging, both reproductive fitness
and mitochondrial homeostasis decline. Mitochondrial metabolism and dynamics are key …
and mitochondrial homeostasis decline. Mitochondrial metabolism and dynamics are key …
Oxidative stress and reproductive function: oxidative stress and in vitro ageing of the post-ovulatory oocyte: an update on recent advances in the field
In brief Post-ovulatory ageing of oocytes leads to poor oocyte and embryo quality as well as
abnormalities in offspring. This review provides an update on the contributions of oxidative …
abnormalities in offspring. This review provides an update on the contributions of oxidative …
Obesity and oocyte quality: significant implications for ART and emerging mechanistic insights
The prevalence of obesity in adults worldwide, and specifically in women of reproductive
age, is concerning given the risks to fertility posed by the increased risk of type 2 diabetes …
age, is concerning given the risks to fertility posed by the increased risk of type 2 diabetes …
[HTML][HTML] Mitochondria in oocyte aging: current understanding
D Zhang, D Keilty, ZF Zhang… - Facts, views & vision in …, 2017 - ncbi.nlm.nih.gov
The oocyte is the largest cell found in multicellular organisms. Mitochondria, as the energy
factories for cells, are found in high numbers in oocytes, as they provide the energy for …
factories for cells, are found in high numbers in oocytes, as they provide the energy for …
Resveratrol provides neuroprotective effects through modulation of mitochondrial dynamics and ERK1/2 regulated autophagy
KL Lin, KJ Lin, PW Wang, JH Chuang, HY Lin… - Free radical …, 2018 - Taylor & Francis
Mitochondrial dysfunction and oxidative stress are underlying contributors to Parkinson's
disease (PD). The reduction of aberrant proteins and dysfunctional mitochondria through …
disease (PD). The reduction of aberrant proteins and dysfunctional mitochondria through …