Reversible osmotic blood-brain barrier disruption in humans: implications for the chemotherapy of malignant brain tumors

EA Neuwelt, EP Frenkel, J Diehl, LH Vu… - …, 1980 - journals.lww.com
The blood-brain barrier seems to be an important factor in drug access to malignant brain
tumors. Successful experimental reversible disruption of the blood-brain barrier in animals …

Maculopathy associated with combination chemotherapy and osmotic opening of the blood-brain barrier

RH Millay, ML Klein, WT Shults, SA Dahlborg… - American journal of …, 1986 - Elsevier
Eleven patients with intracranial malignant neoplasms underwent hyperosmotic opening of
the blood-brain barrier by rapid mannitol infusion via the internal carotid or vertebral artery …

Osmotic opening of blood-brain and blood-ocular barriers

SI Rapoport - Experimental Eye Research, 1977 - Elsevier
Barriers in the eye and brain are composed of layers of cells that are connected by tight
junctions which restrict intercellular diffusion. Exposure to hypertonie solutions increases the …

Proof that the ciliary epithelium can regenerate

H Yamashita, M Sears - Experimental Eye Research, 1978 - Elsevier
Regeneration of the ciliary epithelium after cryo injury was investigated by light and electron
microscopy. In addition, autoradiography done after [3 H] thymidine incorporation, and …

Ultrasound biomicroscopic view of detachment of the ciliary epithelium in retinal detachment with atopic dermatitis

S Yoshida, M Sasoh, M Arima, Y Uji - Ophthalmology, 1997 - Elsevier
Purpose: The authors evaluated the effectiveness of ultrasound biomicroscopy to determine
the condition of the ciliary body during perioperative examinations of patients with atopic …

Volume regulation of non-pigmented cells from ciliary epithelium.

NA Farahbakhsh, GL Fain - Investigative ophthalmology & …, 1987 - iovs.arvojournals.org
We describe a new method for investigating ion and water transport in ciliary epithelium. A
single ciliary process from the rabbit is isolated, placed in a chamber, and rapidly perfused …

Effect of intravenous mannitol on intraocular pressure in vitrectomized silicone-oil-filled eyes

B Takkar, P Chandra, R Shah, I Bhatia… - Seminars in …, 2017 - Taylor & Francis
Purpose: To evaluate the effect of intravenous mannitol (IVM) on intraocular pressure (IOP)
in vitrectomized eyes. Methods: Thirty-one patients with raised IOP after retinal surgery with …

[PDF][PDF] NBO and topology (MESP, ELF, LOL) analysis of 2-hydroxypropanamide

K Rajalakshmi, M Vetrivel - INTERNATIONAL JOURNAL, 2020 - ijasret.com
In the present work, the optimized molecular geometry of 2-Hydroxypropanamide calculated
by DFT/B3LYP method with 6-31 G (d, p) basis set has been computationally investigated for …

Increased aqueous flare as a result of a therapeutic dose of mannitol in humans

K Miyake, Y Miyake, K Maekubo - Graefe's archive for clinical and …, 1992 - Springer
To evaluate the effects of mannitol on aqueous flare (aqueous protein concentration), we
administered an intravenous clinical therapeutic dose to normal young adults (average age …

Long-term ocular effects of osmotic modification of the blood-brain barrier in monkeys. I. Clinical examinations; aqueous ascorbate and protein.

DE Gaasterland, JA Barranger… - … & Visual Science, 1983 - iovs.arvojournals.org
The blood-aqueous humor barrier in adult rhesus monkeys was opened by intracarotid
infusion of a 25% mannitol solution. Each monkey had one to four infusions into the same …