[HTML][HTML] Brain–gut–microbiota axis in depression: A historical overview and future directions

L Chang, Y Wei, K Hashimoto - Brain Research Bulletin, 2022 - Elsevier
Depression is the most common mental disorder and a leading cause of disability
worldwide. Despite abundant research, the precise mechanisms underlying the …

[HTML][HTML] Recognizing the role of the vagus nerve in depression from microbiota-gut brain axis

C Tan, Q Yan, Y Ma, J Fang, Y Yang - Frontiers in Neurology, 2022 - frontiersin.org
Depression is a worldwide disease causing severe disability, morbidity, and mortality.
Despite abundant studies, the precise mechanisms underlying the pathophysiology of …

[HTML][HTML] Gut microbiome-wide association study of depressive symptoms

D Radjabzadeh, JA Bosch, AG Uitterlinden… - Nature …, 2022 - nature.com
Depression is one of the most poorly understood diseases due to its elusive pathogenesis.
There is an urgency to identify molecular and biological mechanisms underlying depression …

Multi-strain probiotic formulation reverses maternal separation and chronic unpredictable mild stress-generated anxiety-and depression-like phenotypes by …

MP Dandekar, MSK Palepu, S Satti… - ACS Chemical …, 2022 - ACS Publications
Depression is a debilitating mental disorder that affects> 322 million people worldwide.
Despite the availability of several antidepressant agents, many patients remain treatment …

[HTML][HTML] Gut microbiota in anxiety and depression: unveiling the relationships and management options

A Kumar, J Pramanik, N Goyal, D Chauhan… - Pharmaceuticals, 2023 - mdpi.com
The gut microbiota is critical for maintaining human health and the immunological system.
Several neuroscientific studies have shown the significance of microbiota in developing …

Role of gut microbiota in depression: Understanding molecular pathways, recent research, and future direction

D Rathour, S Shah, S Khan, PK Singh… - Behavioural brain …, 2023 - Elsevier
Gut microbiota, also known as the “second brain” in humans because of the regulatory role it
has on the central nervous system via neuronal, chemical and immune pathways. It has …

[HTML][HTML] Clinical significance of microbiota changes under the influence of psychotropic drugs. An updated narrative review

A Misera, I Łoniewski, J Palma, M Kulaszyńska… - Frontiers in …, 2023 - frontiersin.org
Relationship between drugs and microbiota is bilateral. Proper composition thus function of
microbiota is a key to some medications used in modern medicine. However, there is also …

[HTML][HTML] Th17 cells sense microbiome to promote depressive-like behaviors

EM Medina-Rodriguez, J Watson, J Reyes, M Trivedi… - Microbiome, 2023 - Springer
Background Microbiome alterations have been associated with depression, and fecal
transfer of depressed patients' microbiomes is sufficient to enhance despair behaviors in …

[HTML][HTML] The gut microbiota, HPA axis, and brain in adolescent-onset depression: Probiotics as a novel treatment

D Freimer, TT Yang, TC Ho, O Tymofiyeva… - Brain, Behavior, & …, 2022 - Elsevier
Stress-associated disruptions in the development of frontolimbic regions may play a critical
role in the emergence of adolescent-onset depression. These regions are particularly …

[HTML][HTML] A complete guide to human microbiomes: Body niches, transmission, development, dysbiosis, and restoration

J Reynoso-García, AE Miranda-Santiago… - Frontiers in Systems …, 2022 - frontiersin.org
Humans are supra-organisms co-evolved with microbial communities (Prokaryotic and
Eukaryotic), named the microbiome. These microbiomes supply essential ecosystem …