The endothelium acts as the barrier that prevents circulating lipids such as lipoproteins and
fatty acids into the arterial wall; it also regulates normal functioning in the circulatory system …

Abstract Hypoxia-inducible factor 1 (HIF-1) activates the transcription of genes that are
involved in crucial aspects of cancer biology, including angiogenesis, cell survival, glucose …

Pancreatic ductal adenocarcinoma (PDAC) is a lethal disease with high resistance to
therapies. Inflammatory and immunomodulatory signals co-exist in the pancreatic tumour …

Accumulating evidence has shown that the hypoxic microenvironment, which is critical
during cancer development, plays a key role in regulating breast cancer progression and …

Myeloid‐derived suppressor cells (MDSCs) promote tumor progression. The mechanisms of
MDSC development during tumor growth remain unknown. Tumor exosomes (T‐exosomes) …

Growing evidence indicates that inflammation is a contributing factor leading to cancer
development. However, pathways involved in this progression are not well understood. To …

Mitochondrial dysfunction resulting in oxidative stress could be associated with tissue and
cell damage common in many T cell-mediated autoimmune diseases. Autoreactive CD4 T …

Abstract Hypoxia-inducible factor 1 (HIF-1) regulates many genes induced by low oxygen
conditions. The expression of important hypoxic genes such as glucose transporter 1 and …

Menstruation has many of the features of an inflammatory process. The complexity and
sequence of inflammatory-type events leading to the final tissue breakdown and bleeding …

Angiogenesis is required for multistage carcinogenesis. The inducible enzyme
cyclooxygenase-2 (COX-2) is an important mediator of angiogenesis and tumor growth …