Despite numerous animal trials reporting that cell therapy promotes collateral flow, clinical
trials have not convincingly shown benefit. Patient-related risk factors are often used to …

Properly regulated angiogenesis and arteriogenesis are essential for effective wound
healing. Tissue injury induces robust new vessel formation and subsequent vessel …

Coronary collateralization is substantially impaired in patients with type 2 diabetes and
occlusive coronary artery disease, which leads to aggravated myocardial ischemia and a …

BACKGROUND: Restoring the capacity of endothelial progenitor cells (EPCs) to promote
angiogenesis is the major therapeutic strategy of diabetic peripheral artery disease. The aim …

We previously reported that ethanol (EtOH) stimulates endothelial angiogenic activity
mediated via a notch-and angiopoietin-1 (Ang-1) pathway. As crosstalk exists between …

Arterial lumen narrowing and vascular occlusion is the actual cause of morbidity and
mortality in atherosclerotic disease. Collateral artery formation (arteriogenesis) refers to an …

OBJECTIVE: Angiogenesis is the growth and proliferation of blood vessels from existing
vascular structures, and therapeutic angiogenesis seeks to promote blood vessel growth to …

This study aimed to show the significance of capillary function in post-ischemic recovery
from the perspective of physiological parameters, such as blood flow, hemoglobin …

Aims Angiogenesis is compromised under conditions of hypercholesterolaemia. Since
disturbed angiogenesis predisposes to ischaemic injuries, efforts have been made to …

Indocyanine green (ICG) fluorescence imaging has been clinically used for noninvasive
visualizations of vascular structures. We have previously developed a diagnostic system …