Mesenchymal stromal cells for improvement of cardiac function following acute myocardial infarction: a matter of timing

S Barrère-Lemaire, A Vincent… - Physiological …, 2024 - journals.physiology.org
Acute myocardial infarction (AMI) is the leading cause of cardiovascular death and remains
the most common cause of heart failure. Reopening of the occluded artery, ie, reperfusion, is …

[HTML][HTML] Macrophage-based therapeutic approaches for cardiovascular diseases

M Sansonetti, B Al Soodi, T Thum, M Jung - Basic Research in Cardiology, 2024 - Springer
Despite the advances in treatment options, cardiovascular disease (CVDs) remains the
leading cause of death over the world. Chronic inflammatory response and irreversible …

[HTML][HTML] Epigenetic regulation of fibroblasts and crosstalk between Cardiomyocytes and Non-myocyte cells in Cardiac Fibrosis

L Chu, D Xie, D Xu - Biomolecules, 2023 - mdpi.com
Epigenetic mechanisms and cell crosstalk have been shown to play important roles in the
initiation and progression of cardiac fibrosis. This review article aims to provide a thorough …

Macrophage heterogeneity and its impact on myocardial ischemia-reperfusion injury: an integrative review

S Xu, C Xu, J Xu, K Zhang, H Zhang - Journal of Inflammation …, 2023 - Taylor & Francis
The coronary reperfusion following acute myocardial infarction can paradoxically trigger
myocardial ischemia-reperfusion (IR) injury. This complex phenomenon involves the …

[HTML][HTML] Macrophages in cardiovascular diseases: molecular mechanisms and therapeutic targets

R Chen, H Zhang, B Tang, Y Luo, Y Yang… - … and Targeted Therapy, 2024 - nature.com
The immune response holds a pivotal role in cardiovascular disease development. As
multifunctional cells of the innate immune system, macrophages play an essential role in …

[HTML][HTML] The Role of Macrophages in Cardiac Function and Disease

N Prevete, D Sorriento - Journal of Molecular Pathology, 2023 - mdpi.com
A tight association between inflammation and cardiac damage has been extensively
recognized. In this review, we will focus on macrophages as key players in the physiology …

Stimuli‐Mediated Macrophage Switching, Unraveling the Dynamics at the Nanoplatforms–Macrophage Interface

K Ganguly, R Luthfikasari, A Randhawa… - Advanced …, 2024 - Wiley Online Library
Macrophages play an essential role in immunotherapy and tissue regeneration owing to
their remarkable plasticity and diverse functions. Recent bioengineering developments have …

[HTML][HTML] M6A regulator methylation patterns and characteristics of immunity in acute ST-segment elevation myocardial infarction

J Yang, Q Shangguan, G Xie, M Yang, G Sheng - Scientific Reports, 2023 - nature.com
M6A methylation is the most prevalent and abundant RNA modification in mammals.
Although there are many studies on the regulatory role of m6A methylation in the immune …

[HTML][HTML] Communication molecules (ncRNAs) mediate tumor-associated macrophage polarization and tumor progression

M Yao, X Mao, Z Zhang, F Cui, S Shao… - Frontiers in Cell and …, 2024 - frontiersin.org
Non-coding RNAs play important roles in tumor cells and macrophages and participate in
their communication as messengers. Non-coding RNAs have an impact in tumor cell …

A novel 14-amino acid peptide from yak alleviates kidney damage in the rat model of myocardial ischemia-reperfusion

D Qin, Z Hu, F Yang, T Xie, Q Wu, H Lu, W Guo, X Wu… - Food Bioscience, 2024 - Elsevier
Myocardial ischemia-reperfusion (MI/R) not only causes cardiac damage, but also causes
severe renal damage. T8 is the 8th peptide identified by peptiomics in digested yak milk …