Far-red fluorescent probes for canonical and non-canonical nucleic acid structures: current progress and future implications

YV Suseela, N Narayanaswamy, S Pratihar… - Chemical Society …, 2018 - pubs.rsc.org
The structural diversity and functional relevance of nucleic acids (NAs), mainly
deoxyribonucleic acid (DNA) and ribonucleic acid (RNA), are indispensable for almost all …

[HTML][HTML] G-quadruplex-based fluorescent turn-on ligands and aptamers: from development to applications

MI Umar, D Ji, CY Chan, CK Kwok - Molecules, 2019 - mdpi.com
Guanine (G)-quadruplexes (G4s) are unique nucleic acid structures that are formed by
stacked G-tetrads in G-rich DNA or RNA sequences. G4s have been reported to play …

Guidelines for G-quadruplexes: I. In vitro characterization

Y Luo, A Granzhan, J Marquevielle, A Cucchiarini… - Biochimie, 2023 - Elsevier
Besides the well-known DNA double-helix, non-canonical nucleic acid structures regulate
crucial biological activities. Among these oddities, guanine-rich DNA sequences can form …

Visualizing the quadruplex: from fluorescent ligands to light-up probes

E Largy, A Granzhan, F Hamon, D Verga… - Quadruplex Nucleic …, 2013 - Springer
Detection of quadruplex structures by visual methods is a major challenge of the quadruplex
nucleic acid research area. Consequently, considerable efforts are under way for the …

Recent trends in biosensors based on electrochemical and optical techniques for cyanobacterial neurotoxin detection

JA Park, Y Seo, H Sohn, C Park, J Min, T Lee - BioChip Journal, 2022 - Springer
Cyanobacteria that cause algal blooms are distributed worldwide and have been reported
for a long time. Further, cyanobacterial growth is increasingly spreading because of …

Fluorescence light-up probe for parallel G-quadruplexes

B Jin, X Zhang, W Zheng, X Liu, C Qi, F Wang… - Analytical …, 2014 - ACS Publications
Putative G-quadruplex-forming sequences (PQS) are highly prevalent in human genome;
however, the structures and functions of most PQSs in genome are poorly understood …

[HTML][HTML] Cleavage-based signal amplification of RNA

Y Zhao, L Zhou, Z Tang - Nature communications, 2013 - nature.com
RNA detection has become an integral part of current biomedical research. Up to now, the
reverse transcription–PCR has been the most practical method to detect mRNA targets …

Molecular engineering of thiazole orange dye: Change of fluorescent signaling from universal to specific upon binding with nucleic acids in bioassay

YJ Lu, Q Deng, JQ Hou, DP Hu, ZY Wang… - ACS Chemical …, 2016 - ACS Publications
The universal fluorescent staining property of thiazole orange (TO) dye was adapted in order
to be specific for G-quadruplex DNA structures, through the introduction of a styrene-like …

Aptamer biosensor for label-free impedance spectroscopy detection of potassium ion based on DNA G-quadruplex conformation

Z Chen, L Chen, H Ma, T Zhou, X Li - Biosensors and Bioelectronics, 2013 - Elsevier
Herein, a label-free and highly sensitive electrochemical impedance spectroscopy (EIS)
aptasensor for the detection of potassium ion (K+) was developed based on a …

Design of a fluorescent DNA IMPLICATION logic gate and detection of Ag+ and cysteine with triphenylmethane dye/G-quadruplex complexes

JH Guo, DM Kong, HX Shen - Biosensors and bioelectronics, 2010 - Elsevier
This paper describes the construction of a DNA IMPLICATION logic gate based on
triphenylmethane (TPM) dye/G-quadruplex complexes, using Ag+ and cysteine (Cys) as the …