Intranasal vaccines for SARS-CoV-2: From challenges to potential in COVID-19 management

VP Chavda, LK Vora, AK Pandya, VB Patravale - Drug discovery today, 2021 - Elsevier
Abstract Unlike conventional Coronavirus 2019 (COVID-19) vaccines, intranasal vaccines
display a superior advantage because the nasal mucosa is often the initial site of infection …

Nanoparticle-based delivery systems for vaccines

R Bezbaruah, VP Chavda, L Nongrang, S Alom… - Vaccines, 2022 - mdpi.com
Vaccination is still the most cost-effective way to combat infectious illnesses. Conventional
vaccinations may have low immunogenicity and, in most situations, only provide partial …

Microneedle array systems for long-acting drug delivery

LK Vora, K Moffatt, IA Tekko, AJ Paredes… - European Journal of …, 2021 - Elsevier
The development of microneedles (MNs) assisted drug delivery technologies have been
highly active for more than two decades. The minimally invasive and self-administered MN …

Recent review of COVID-19 management: Diagnosis, treatment and vaccination

VP Chavda, S Vuppu, T Mishra, S Kamaraj… - Pharmacological …, 2022 - Springer
The idiopathic Coronavirus disease 2019 (COVID-19) pandemic outbreak caused by the
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has reached global …

Age-related risk factors and complications of patients with COVID-19: a population-based retrospective study

H Zhang, Y Wu, Y He, X Liu, M Liu, Y Tang, X Li… - Frontiers in …, 2022 - frontiersin.org
Objective: To study the differences in clinical characteristics, risk factors, and complications
across age-groups among the inpatients with the coronavirus disease 2019 (COVID-19) …

The Impact of Vaccination on COVID-19 Burden of Disease in the Adult and Elderly Population: A Systematic Review of Italian Evidence

GE Calabrò, C Pappalardo, F D'Ambrosio, M Vece… - Vaccines, 2023 - mdpi.com
COVID-19 is a major global health threat, with millions of confirmed cases and deaths
worldwide. Containment and mitigation strategies, including vaccination, have been …

The importance of nutritional status on clinical outcomes among both ICU and Non-ICU patients with COVID-19

A Pourmahmoudi, J Nicolau, N Veronese… - Clinical Nutrition …, 2022 - Elsevier
Background and aims The current Covid-19 outbreak becomes a tremendous public health
concern worldwide. Since a little information is available on nutritional status and its …

The mechanisms of zinc action as a potent anti-viral agent: the clinical therapeutic implication in COVID-19

AS Prasad, A Malysa, G Bepler, A Fribley, B Bao - Antioxidants, 2022 - mdpi.com
The pandemic of COVID-19 was caused by a novel coronavirus termed as SARS-CoV2 and
is still ongoing with high morbidity and mortality rates in the whole world. The pathogenesis …

[HTML][HTML] Resources and computational strategies to advance small molecule SARS-CoV-2 discovery: Lessons from the pandemic and preparing for future health …

N Singh, BO Villoutreix - Computational and Structural Biotechnology …, 2021 - Elsevier
There is an urgent need to identify new therapies that prevent SARS-CoV-2 infection and
improve the outcome of COVID-19 patients. This pandemic has thus spurred intensive …

Discovery and structural optimization of 3-O-β-chacotriosyl oleanane-type triterpenoids as potent entry inhibitors of SARS-CoV-2 virus infections

H Li, C Cheng, S Li, Y Wu, Z Liu, M Liu, J Chen… - European Journal of …, 2021 - Elsevier
Abstract Currently, SARS-CoV-2 virus is an emerging pathogen that has posed a serious
threat to public health worldwide. However, no agents have been approved to treat SARS …