Quantification of lung PET images: challenges and opportunities
Millions of people are affected by respiratory diseases, leading to a significant health burden
globally. Because of the current insufficient knowledge of the underlying mechanisms that …
globally. Because of the current insufficient knowledge of the underlying mechanisms that …
Assessment of Lung Inflammation With 18F-FDG PET During Acute Lung Injury
N de Prost, MR Tucci, MFV Melo - American Journal of …, 2010 - Am Roentgen Ray Soc
OBJECTIVE. The purpose of this review is to describe the current experimental and clinical
data regarding the fundamentals and applications of 18F-FDG PET during acute lung injury …
data regarding the fundamentals and applications of 18F-FDG PET during acute lung injury …
In vivo imaging of invasive aspergillosis with 18F-fluorodeoxysorbitol positron emission tomography
Invasive aspergillosis is a critical complication in immunocompromised patients with
hematologic malignancies or with viral pneumonia caused by influenza virus or SARS‑CoV …
hematologic malignancies or with viral pneumonia caused by influenza virus or SARS‑CoV …
A novel neutrophil-specific PET imaging agent: cFLFLFK-PEG-64Cu
The synthesis and validation of a new, highly potent 64Cu-labeled peptide, cFLFLFK-PEG-
64Cu, that targets the formyl peptide receptor (FPR) on leukocytes is described. The peptide …
64Cu, that targets the formyl peptide receptor (FPR) on leukocytes is described. The peptide …
Regional gas exchange and cellular metabolic activity in ventilator-induced lung injury
Background Alveolar overdistension and repetitive derecruitment-recruitment contribute to
ventilator-induced lung injury (VILI). The authors investigated (1) whether inflammatory cell …
ventilator-induced lung injury (VILI). The authors investigated (1) whether inflammatory cell …
Quantifying pulmonary inflammation in cystic fibrosis with positron emission tomography
DL Chen, TW Ferkol, MA Mintun, JE Pittman… - American journal of …, 2006 - atsjournals.org
Rationale: Although infection contributes to morbidity in patients with cystic fibrosis (CF), the
host inflammatory response is also an important cause of progressive pulmonary function …
host inflammatory response is also an important cause of progressive pulmonary function …
Approaches to evaluate lung inflammation in translational research
Inflammation is a common feature in several types of lung disease and is a frequent end
point to validate lung disease models, evaluate genetic or environmental impact on disease …
point to validate lung disease models, evaluate genetic or environmental impact on disease …
FDG-PET imaging of pulmonary inflammation in healthy volunteers after airway instillation of endotoxin
DL Chen, DB Rosenbluth, MA Mintun… - Journal of Applied …, 2006 - journals.physiology.org
Recent studies indicate that a focal, limited, inflammatory response can be safely elicited
after direct bronchial instillation of small doses of endotoxin into a single lung segment …
after direct bronchial instillation of small doses of endotoxin into a single lung segment …
Visualizing lung function with positron emission tomography
RS Harris, DP Schuster - Journal of applied physiology, 2007 - journals.physiology.org
Positron emission tomography (PET) provides three-dimensional images of the distributions
of radionuclides that have been inhaled or injected into the lungs. By using radionuclides …
of radionuclides that have been inhaled or injected into the lungs. By using radionuclides …
Imaging the injured lung: mechanisms of action and clinical use
Acute respiratory distress syndrome (ARDS) consists of acute hypoxemic respiratory failure
characterized by massive and heterogeneously distributed loss of lung aeration caused by …
characterized by massive and heterogeneously distributed loss of lung aeration caused by …