Emerging approaches for restoration of hearing and vision

S Kleinlogel, C Vogl, M Jeschke, J Neef… - Physiological …, 2020 - journals.physiology.org
Impairments of vision and hearing are highly prevalent conditions limiting the quality of life
and presenting a major socioeconomic burden. For a long time, retinal and cochlear …

Formation, structure, and function of extra‐skeletal bones in mammals

A Nasoori - Biological Reviews, 2020 - Wiley Online Library
This review describes the formation, structure, and function of bony compartments in antlers,
horns, ossicones, osteoderm and the os penis/os clitoris (collectively referred to herein as …

Human auditory ossicles as an alternative optimal source of ancient DNA

K Sirak, D Fernandes, O Cheronet, E Harney… - Genome …, 2020 - genome.cshlp.org
DNA recovery from ancient human remains has revolutionized our ability to reconstruct the
genetic landscape of the past. Ancient DNA research has benefited from the identification of …

Neural crest contributions to the ear: implications for congenital hearing disorders

KE Ritter, DM Martin - Hearing research, 2019 - Elsevier
Congenital hearing disorders affect millions of children worldwide and can significantly
impact acquisition of speech and language. Efforts to identify the developmental genetic …

Does 3-T fetal MRI induce adverse acoustic effects in the neonate? A preliminary study comparing postnatal auditory test performance of fetuses scanned at 1.5 and 3 …

C Jaimes, J Delgado, MB Cunnane, HL Hedrick… - Pediatric …, 2019 - Springer
Abstract Background Fetal MRI at 3 T is associated with increased acoustic noise relative to
1.5 T. Objective The goal of this study is to determine if there is an increased prevalence of …

Novel imaging techniques to study postmortem human fetal anatomy: a systematic review on microfocus-CT and ultra-high-field MRI

Y Dawood, GJ Strijkers, J Limpens, RJ Oostra… - European …, 2020 - Springer
Background MRI and CT have been extensively used to study fetal anatomy for research
and diagnostic purposes, enabling minimally invasive autopsy and giving insight in human …

First evidence of the link between internal and external structure of the human inner ear otolith system using 3D morphometric modeling

CM Smith, IS Curthoys, JT Laitman - Scientific Reports, 2023 - nature.com
Our sense of balance is among the most central of our sensory systems, particularly in the
evolution of human positional behavior. The peripheral vestibular system (PVS) comprises …

(−)-Epigallocatechin-3-gallate (EGCG) prevents aminoglycosides-induced ototoxicity via anti-oxidative and anti-apoptotic pathways

Y Zong, F Chen, S Li, H Zhang - International Journal of Pediatric …, 2021 - Elsevier
Objectives Aminoglycoside-induced cochlear ototoxicity causes inner ear hair cells (HCs)
loss and leads to hearing impairment in patients, but no treatment completely eliminates the …

Influence of physical activity before and during pregnancy on infant's sleep and neurodevelopment at 1-year-old

K Nakahara, T Michikawa, S Morokuma, M Ogawa… - Scientific reports, 2021 - nature.com
The aim of this study was to investigate the association between maternal physical activity
(PA) before and during pregnancy and sleep and developmental problems in 1-year-old …

Current advances in Adeno-Associated virus-mediated gene therapy to prevent acquired hearing loss

F Wu, K Sambamurti, S Sha - Journal of the Association for Research in …, 2022 - Springer
Adeno-associated viruses (AAVs) are viral vectors that offer an excellent platform for gene
therapy due to their safety profile, persistent gene expression in non-dividing cells, target …