Chronic traumatic encephalopathy (CTE) is a neurodegenerative disease associated with a
history of repetitive head impacts (RHI). CTE was described in boxers as early as the 1920s …

Region of interest (ROI) volumetric assessment has become a standard technique in
quantitative neuroimaging. ROI volume is thought to represent a coarse proxy for making …

The glymphatic system functions in the removal of potentially harmful metabolites and
proteins from the brain. Dynamic, contrast-enhanced MRI was used in fully awake rats to …

The clinical translation of therapeutic approaches to combat debilitating neurodegenerative
conditions, such as Parkinson's disease (PD), remains as an urgent unmet challenge. The …

Up to 50% of traumatic brain injury (TBI) survivors demonstrate persisting and late-onset
anxiety disorders indicative of limbic system dysregulation, yet the pathophysiology …

Mild traumatic brain injury (TBI) results in chronic affective disorders such as depression,
anxiety, and fear that persist up to years following injury and significantly impair the quality of …

Traumatic brain injury (TBI) is a leading cause of death and disability worldwide. Despite
extensive research efforts, the majority of trialed monotherapies to date have failed to …

Introduction Repetitive subconcussive head impacts can lead to subtle neural changes and
functional consequences on brain health. However, the objective assessment of these …

Traumatic brain injury (TBI) and spinal cord injury (SCI) present a significant contribution to
the global disease burden. White matter tracts are susceptible to both the physical forces of …

Penetrating cortical impact injuries alter neuronal communication beyond the injury
epicentre, across regions involved in affective, sensorimotor and cognitive processing …