How do plants defend themselves against pathogens-Biochemical mechanisms and genetic interventions

S Kaur, MK Samota, M Choudhary… - … and Molecular Biology …, 2022 - Springer
In agro-ecosystem, plant pathogens hamper food quality, crop yield, and global food
security. Manipulation of naturally occurring defense mechanisms in host plants is an …

Gut microbiota-derived metabolites in the regulation of host immune responses and immune-related inflammatory diseases

W Yang, Y Cong - Cellular & molecular immunology, 2021 - nature.com
The gut microbiota has a critical role in the maintenance of immune homeostasis. Alterations
in the intestinal microbiota and gut microbiota-derived metabolites have been recognized in …

Gut microbiota, metabolites and host immunity

MG Rooks, WS Garrett - Nature reviews immunology, 2016 - nature.com
The microbiota—the collection of microorganisms that live within and on all mammals—
provides crucial signals for the development and function of the immune system. Increased …

[HTML][HTML] Metabolite interactions between host and microbiota during health and disease: Which feeds the other?

Y Zhang, R Chen, DD Zhang, S Qi, Y Liu - Biomedicine & Pharmacotherapy, 2023 - Elsevier
Metabolites produced by the host and microbiota play a crucial role in how human bodies
develop and remain healthy. Most of these metabolites are produced by microbiota and …

The gut microbiota, bacterial metabolites and colorectal cancer

P Louis, GL Hold, HJ Flint - Nature reviews microbiology, 2014 - nature.com
Accumulating evidence suggests that the human intestinal microbiota contributes to the
aetiology of colorectal cancer (CRC), not only via the pro-carcinogenic activities of specific …

Human gut bacteria as potent class I histone deacetylase inhibitors in vitro through production of butyric acid and valeric acid

S Yuille, N Reichardt, S Panda, H Dunbar, IE Mulder - PloS one, 2018 - journals.plos.org
Overexpression of histone deacetylase (HDAC) isoforms has been implicated in a variety of
disease pathologies, from cancer and colitis to cardiovascular disease and …

Polyamines and gut microbiota

R Tofalo, S Cocchi, G Suzzi - Frontiers in nutrition, 2019 - frontiersin.org
The microbiota of gut is the community of microbes living in an individual's gastrointestinal
tract. Several bacterial genera and species act in a concerted manner to establish metabolic …

Bridging intestinal immunity and gut microbiota by metabolites

G Wang, S Huang, Y Wang, S Cai, H Yu, H Liu… - Cellular and Molecular …, 2019 - Springer
The gastrointestinal tract is the site of nutrient digestion and absorption and is also colonized
by diverse, highly mutualistic microbes. The intestinal microbiota has diverse effects on the …

Gut microbiota in systemic lupus erythematosus: A fuse and a solution

Y Chen, J Lin, L Xiao, X Zhang, L Zhao, M Wang… - Journal of …, 2022 - Elsevier
Gut commensals help shape and mold host immune system and deeply influence human
health. The disease spectrum of mankind that gut microbiome may associate with is ever …

Polyamines: double agents in disease and plant immunity

L Gerlin, C Baroukh, S Genin - Trends in Plant Science, 2021 - cell.com
Polyamines (PAs) are ubiquitous amine molecules found in all living organisms. In plants,
beside their role in signaling and protection against abiotic stresses, there is increasing …