Primary sclerosing cholangitis

JK Dyson, U Beuers, DEJ Jones, AW Lohse, M Hudson - The Lancet, 2018 - thelancet.com
Primary sclerosing cholangitis is a rare, chronic cholestatic liver disease characterised by
intrahepatic or extrahepatic stricturing, or both, with bile duct fibrosis. Inflammation and …

[HTML][HTML] IgG4-related sclerosing cholangitis and primary sclerosing cholangitis

A Tanaka - Gut and liver, 2019 - ncbi.nlm.nih.gov
Sclerosing cholangitis (SC) is defined as a condition with progressive stenosis and
destruction of the bile ducts due to diffuse inflammation and fibrosis and currently includes …

Clinical features, response to treatment, and outcomes of IgG4-related sclerosing cholangitis

A Tanaka, S Tazuma, K Okazaki, T Nakazawa… - Clinical …, 2017 - Elsevier
Background & Aims Immunoglobulin G4 sclerosing cholangitis (IgG4-SC) is a biliary tract
manifestation of IgG4-related systemic disease. We investigated the demographics, clinical …

Autoimmune hepatitis, sclerosing cholangitis, and autoimmune sclerosing cholangitis or overlap syndrome

N Kerkar, A Chan - Clinics in liver disease, 2018 - liver.theclinics.com
Autoimmune liver disease in pediatrics encompasses autoimmune hepatitis (AIH),
autoimmune overlap with sclerosing cholangitis (SC), recurrence of AIH after liver …

No negative impact of serum IgG4 levels on clinical outcome in 435 patients with primary sclerosing cholangitis from Japan

A Tanaka, S Tazuma, T Nakazawa… - Journal of Hepato …, 2017 - Wiley Online Library
Background Several studies have demonstrated that elevated serum IgG4 levels are
associated with poor outcomes of primary sclerosing cholangitis (PSC), but the impact of …

Development of a scoring system for differentiating IgG4-related sclerosing cholangitis from primary sclerosing cholangitis

SH Moon, MH Kim, JK Lee, S Baek, YS Woo… - Journal of …, 2017 - Springer
Background Recent research has shown that a substantial number of patients with primary
sclerosing cholangitis (PSC) can also have elevated serum/tissue IgG4. The aim of our study …

New therapies target the toxic consequences of cholestatic liver disease

PLM Jansen - Expert Review of Gastroenterology & Hepatology, 2018 - Taylor & Francis
Introduction: In most cholestatic liver diseases the primary cholestasis-causing lesions are
located in the biliary tree and may be of (auto) immune origin. Bile salts are responsible for …

Comparative clinical characteristics and natural history of three variants of sclerosing cholangitis: IgG4-related SC, PSC/AIH and PSC alone

M Lian, B Li, X Xiao, Y Yang, P Jiang, L Yan, C Sun… - Autoimmunity …, 2017 - Elsevier
There is increased interest and recognition of the clinical variants of Sclerosing Cholangitis
(SC) namely IgG4-SC, PSC/AIH overlap and PSC. For most Centers, the characteristic of …

Shifting paradigms: what is the true prevalence and clinical course of primary sclerosing cholangitis?

RK Weersma, KD Lindor - Gastroenterology, 2016 - europepmc.org
Shifting Paradigms: What Is the True Prevalence and Clinical Course of Primary Sclerosing
Cholangitis? - Abstract - Europe PMC Sign in | Create an account https://orcid.org Europe PMC …

Clinical utility of personalized serum IgG subclass ratios for the differentiation of IgG4-related sclerosing cholangitis (IgG4-SC) from primary sclerosing cholangitis …

JK Park, D Kim, JM Lee, KH Lee, KT Lee… - Journal of Personalized …, 2022 - mdpi.com
Background: The differential diagnosis of immunoglobulin G4-sclerosing cholangitis (IgG4-
SC) from primary sclerosing cholangitis (PSC) or cholangiocarcinoma (CCA) is important. In …