Sex steroid hormones, hormonal contraception, and the immunobiology of human immunodeficiency virus-1 infection
Z Hel, E Stringer, J Mestecky - Endocrine reviews, 2010 - academic.oup.com
Worldwide, an increasing number of women use oral or injectable hormonal contraceptives.
However, inadequate information is available to aid women and health care professionals in …
However, inadequate information is available to aid women and health care professionals in …
Clinical development of microbicides for the prevention of HIV infection
OJ D'Cruz, FM Uckun - Current pharmaceutical design, 2004 - ingentaconnect.com
The HIV/AIDS pandemic continues its spread at a rate of over 15,000 new infections every
day. Sexual transmission of HIV-1 is the dominant mode of this pandemic spread. For the …
day. Sexual transmission of HIV-1 is the dominant mode of this pandemic spread. For the …
The anti-inflammatory activity of curcumin protects the genital mucosal epithelial barrier from disruption and blocks replication of HIV-1 and HSV-2
Inflammation is a known mechanism that facilitates HIV acquisition and the spread of
infection. In this study, we evaluated whether curcumin, a potent and safe anti-inflammatory …
infection. In this study, we evaluated whether curcumin, a potent and safe anti-inflammatory …
PPARγ and LXR Signaling Inhibit Dendritic Cell-Mediated HIV-1 Capture and trans-Infection
TM Hanley, W Blay Puryear, S Gummuluru… - PLoS …, 2010 - journals.plos.org
Dendritic cells (DCs) contribute to human immunodeficiency virus type 1 (HIV-1)
transmission and dissemination by capturing and transporting infectious virus from the …
transmission and dissemination by capturing and transporting infectious virus from the …
Chlamydia trachomatis Infection of Endocervical Epithelial Cells Enhances Early HIV Transmission Events
LR Buckner, AM Amedee, HL Albritton, PA Kozlowski… - PloS one, 2016 - journals.plos.org
Chlamydia trachomatis causes a predominantly asymptomatic, but generally inflammatory,
genital infection that is associated with an increased risk for HIV acquisition. Endocervical …
genital infection that is associated with an increased risk for HIV acquisition. Endocervical …
Live imaging of HIV-1 transfer across T cell virological synapse to epithelial cells that promotes stromal macrophage infection
During sexual intercourse, HIV-1 crosses epithelial barriers composing the genital mucosa,
a poorly understood feature that requires an HIV-1-infected cell vectoring efficient mucosal …
a poorly understood feature that requires an HIV-1-infected cell vectoring efficient mucosal …
[HTML][HTML] HIV is inactivated after transepithelial migration via adult oral epithelial cells but not fetal epithelial cells
SM Tugizov, R Herrera, P Veluppillai, D Greenspan… - Virology, 2011 - Elsevier
Oral transmission of human immunodeficiency virus (HIV) in adult populations is rare.
However, HIV spread across fetal/neonatal oropharyngeal epithelia could be important in …
However, HIV spread across fetal/neonatal oropharyngeal epithelia could be important in …
Medroxyprogesterone acetate regulates HIV-1 uptake and transcytosis but not replication in primary genital epithelial cells, resulting in enhanced T-cell infection
VH Ferreira, S Dizzell, A Nazli, JK Kafka… - The Journal of …, 2015 - academic.oup.com
Although clinical and experimental evidence indicates that female sex hormones and
hormonal contraceptives regulate susceptibility to human immunodeficiency virus type 1 …
hormonal contraceptives regulate susceptibility to human immunodeficiency virus type 1 …
HIV-1 virological synapse is not simply a copycat of the immunological synapse
The virological synapse (VS) is a tight adhesive junction between an HIV-infected cell and
an uninfected target cell, across which virus can be efficiently transferred from cell to cell in …
an uninfected target cell, across which virus can be efficiently transferred from cell to cell in …
[HTML][HTML] R5-and X4-HIV-1 use differentially the endometrial epithelial cells HEC-1A to ensure their own spread: implication for mechanisms of sexual transmission
H Saïdi, G Magri, N Nasreddine, M Réquena, L Bélec - Virology, 2007 - Elsevier
The mechanism of viral transmission across the mucosal barrier is poorly understood. Using
the endometrial epithelium-derived cell line HEC-1A, we found that the cells are capable of …
the endometrial epithelium-derived cell line HEC-1A, we found that the cells are capable of …