The neural mechanisms and circuitry of the pair bond

H Walum, LJ Young - Nature Reviews Neuroscience, 2018 - nature.com
Love is one of our most powerful emotions, inspiring some of the greatest art, literature and
conquests of human history. Although aspects of love are surely unique to our species …

[HTML][HTML] Reward circuitry dysfunction in psychiatric and neurodevelopmental disorders and genetic syndromes: animal models and clinical findings

GS Dichter, CA Damiano, JA Allen - Journal of neurodevelopmental …, 2012 - Springer
This review summarizes evidence of dysregulated reward circuitry function in a range of
neurodevelopmental and psychiatric disorders and genetic syndromes. First, the …

[HTML][HTML] Intense, passionate, romantic love: a natural addiction? How the fields that investigate romance and substance abuse can inform each other

HE Fisher, X Xu, A Aron, LL Brown - Frontiers in psychology, 2016 - frontiersin.org
Individuals in the early stage of intense romantic love show many symptoms of substance
and non-substance or behavioral addictions, including euphoria, craving, tolerance …

The behavioral, anatomical and pharmacological parallels between social attachment, love and addiction

JP Burkett, LJ Young - Psychopharmacology, 2012 - Springer
Rationale Love has long been referred to as an addiction in literature and poetry. Scientists
have often made comparisons between social attachment processes and drug addiction …

On the psychology of extremism: How motivational imbalance breeds intemperance.

AW Kruglanski, E Szumowska, CH Kopetz… - Psychological …, 2021 - psycnet.apa.org
We present a psychological model of extremism based on the concept of motivational
imbalance whereby a given need gains dominance and overrides other basic concerns. In …

Breaking the loop: oxytocin as a potential treatment for drug addiction

IS McGregor, MT Bowen - Hormones and behavior, 2012 - Elsevier
Drug use typically occurs within a social context, and social factors play an important role in
the initiation, maintenance and recovery from addictions. There is now accumulating …

Why social attachment and oxytocin protect against addiction and stress: insights from the dynamics between ventral and dorsal corticostriatal systems

M Tops, SL Koole, H IJzerman… - Pharmacology …, 2014 - Elsevier
The present article advances a neurobiological model of the reciprocal associations
between social attachment and drug abuse, and social attachment and chronic stress, as …

SHANK3 controls maturation of social reward circuits in the VTA

S Bariselli, S Tzanoulinou, C Glangetas… - Nature …, 2016 - nature.com
Haploinsufficiency of SHANK3, encoding the synapse scaffolding protein SHANK3, leads to
a highly penetrant form of autism spectrum disorder. How SHANK3 insufficiency affects …

Oxytocin receptors are expressed on dopamine and glutamate neurons in the mouse ventral tegmental area that project to nucleus accumbens and other mesolimbic …

J Peris, K MacFadyen, JA Smith… - Journal of …, 2017 - Wiley Online Library
The mesolimbic dopamine (DA) circuitry determines which behaviors are positively
reinforcing and therefore should be encoded in the memory to become a part of the …

[HTML][HTML] Individual differences underlying susceptibility to addiction: Role for the endogenous oxytocin system

FTA Buisman-Pijlman, NM Sumracki, JJ Gordon… - Pharmacology …, 2014 - Elsevier
Recent research shows that the effects of oxytocin are more diverse than initially thought
and that in some cases oxytocin can directly influence the response to drugs and alcohol …