Secondary injury and inflammation after intracerebral haemorrhage: a systematic review and meta-analysis of molecular markers in patient brain tissue

JJM Loan, C Kirby, K Emelianova… - Journal of Neurology …, 2022 - jnnp.bmj.com
Background Inflammatory responses to intracerebral haemorrhage (ICH) are potential
therapeutic targets. We aimed to quantify molecular markers of inflammation in human brain …

Effects of combination treatment of dexamethasone and melatonin on brain injury in intracerebral hemorrhage model in rats

Z Li, G Liang, Y Xue, Y Liu - Brain research, 2009 - Elsevier
The study was performed to investigate the effect of combination therapy with melatonin and
dexamethasone (DEX) on brain injury in intracerebral hemorrhage (ICH) model in rats …

Combination of methylprednisolone and rosiglitazone promotes recovery of neurological function after spinal cord injury

X Li, X Lin, J Du, S Xu, X Lou… - Neural regeneration …, 2016 - journals.lww.com
Methylprednisolone exhibits anti-inflammatory antioxidant properties, and rosiglitazone acts
as an anti-inflammatory and antioxidant by activating peroxisome proliferator-activated …

Peroxisome proliferator-activated receptor-γ agonist rosiglitazone reduces secondary damage in experimental spinal cord injury

X Li, J Du, S Xu, X Lin, Z Ling - Journal of international …, 2013 - journals.sagepub.com
Objective: To investigate the neuroprotective effects of rosiglitazone in a rat traumatic spinal
cord injury (SCI) model. Methods: Adult Sprague–Dawley rats (n ¼ 12/group) underwent …

[引用][C] 高血压脑出血病理及病理生理研究进展

郑毅, 徐学君 - 重庆医学, 2012

Mortality prediction of patients with spontaneous intracerebral hemorrhage by serum soluble Fas ligand concentrations

L Lorente, MM Martín, A Pérez-Cejas… - Expert Review of …, 2022 - Taylor & Francis
Background A study of patients with spontaneous intracerebral hemorrhage (SIH) found a
higher content of Fas ligand in the perihematomic brain area compared to healthy brain …

High serum levels of caspase-3 and early mortality in patients with severe spontaneous intracerebral hemorrhage

L Lorente, MM Martín, A Pérez-Cejas… - Neurocritical Care, 2021 - Springer
Background Apoptotic cell death leads to secondary brain injury after spontaneous
intracerebral hemorrhage (SIH). There is an association between serum caspase-3 levels …

Combination of dexamethasone and aminoguanidine reduces secondary damage in compression spinal cord injury

W Xu, G Lv, Y Wang, X Lu, T Huang, Y Zhu… - Cellular and molecular …, 2009 - Springer
The study was performed to investigate the effect of combination therapy with
aminoguanidine (AG) and dexamethasone (DEX) on the compression spinal cord injury …

Mortality of spontaneous intracerebral haemorrhage patients and high serum caspase-8 concentrations

L Lorente, MM Martín, AF González-Rivero… - … Critical Care & Pain …, 2021 - Elsevier
Purpose Apoptotic changes in brain samples have been found in haematoma areas of
patients with spontaneous intracerebral haemorrhage (SIH) undergoing surgical …

Association between serum levels of caspase-cleaved cytokeratin-18 and early mortality in patients with severe spontaneous intracerebral hemorrhage

L Lorente, MM Martín, A Pérez-Cejas, L Ramos… - BMC neuroscience, 2018 - Springer
Background Apoptotic changes after cerebral hemorrhage in brain samples of humans have
been found. Caspase-cleaved cytokeratin (CCCK)-18 could be detected in the bloodstream …