A series of variously functionalized selenium-containing compounds were purposely
synthesized and evaluated against a panel of cancer cell lines. Most of the compounds …

Radiation damage is an inherent challenge in macromolecular crystallography (MX). This
diminishes the diffraction quality and also compromises the accuracy of the crystal structure …

Oxidative stress surrounding cancer cells provides them with certain growth and survival
advantages necessary for disease progression. In this context, Se-containing molecules …

Selenium (Se) and manganese (Mn) are essential micronutrients that are important
elements of cell metabolism. They are involved in the composition of enzyme systems and …

Leishmaniasis affects more than 12 million humans globally and a further 1 billion people
are at risk in leishmaniasis endemic areas. The lack of a vaccine for leishmaniasis coupled …

The aim of present study was to investigate the anticancer mechanisms of 3, 3′-
diselenodipropionic acid (DSePA), a redox-active organodiselenide in human lung cancer …

Supplementation with selenium is common for dairy cows, but the importance of selenium
source is not clear. This study aimed to compare nano-selenium (Nano-Se) and sodium …

Abstract Series of 2-arylbenzofuran–1, 2, 3-selenodiazole hybrids were prepared via
multiple reactions and then evaluated in vitro through enzymatic assay for inhibitory effect …

Pancreatic ductal adenocarcinoma (PDA) cells reprogram both mitochondrial and lysosomal
functions to support growth. At the same time, this causes significant dishomeostasis of free …

Phthalic selenoanhydride (R-Se) solved in physiological buffer releases various reactive
selenium species including H2Se. It is a potential compound for Se supplementation which …