Irritable bowel syndrome (IBS) is a complex, functional gastrointestinal disorder
characterized by chronic abdominal pain or discomfort and altered bowel habits. Despite the …

The brain-gut axis is a bidirectional communication system between the central nervous
system and the gastrointestinal tract. Serotonin functions as a key neurotransmitter at both …

Background: The awareness is growing that central sensitization is of prime importance for
the assessment and management of chronic pain, but its classification is challenging …

Various peripheral mechanisms have been implicated in the pathogenesis of irritable bowel
syndrome, including intraluminal intestinal irritants, alteration in the bowel microbiome …

Irritable bowel syndrome (IBS) is the most common disorder referred to gastroenterologists
and is characterized by altered bowel habits, abdominal pain, and bloating. Visceral …

The ileal pouch anal anastomosis (IPAA) has revolutionised the surgical management of
ulcerative colitis (UC) and familial adenomatous polyposis (FAP). Despite refinement in …

Background Irritable bowel syndrome (IBS) and other functional bowel disorders (FBDs) are
prevalent disorders with altered microbiota. Prebiotics positively augment gut microbiota and …

Abstract Background and Aim Post‐traumatic stress disorder (PTSD) is a psychiatric
condition characterized by symptoms of hyperarousal and hypervigilance. Increasing …

Irritable bowel syndrome (IBS) is traditionally defined as a functional disorder since it lacks
demonstrable pathological abnormalities. However, in recent years, low grade inflammatory …

The management of visceral pain in patients with disorders of gut–brain interaction, notably
irritable bowel syndrome, presents a considerable clinical challenge, with few available …