[HTML][HTML] Silica nanoparticles: A review of their safety and current strategies to overcome biological barriers

TI Janjua, Y Cao, F Kleitz, M Linden, C Yu… - Advanced Drug Delivery …, 2023 - Elsevier
Silica nanoparticles (SNP) have gained tremendous attention in the recent decades. They
have been used in many different biomedical fields including diagnosis, biosensing and …

Immunotherapy: a promising approach for glioma treatment

F Yasinjan, Y Xing, H Geng, R Guo, L Yang… - Frontiers in …, 2023 - frontiersin.org
Gliomas are the most prevalent primary malignant brain tumors worldwide, with
glioblastoma (GBM) being the most common and aggressive type. Despite two decades of …

Intracavity generation of glioma stem cell–specific CAR macrophages primes locoregional immunity for postoperative glioblastoma therapy

C Chen, W Jing, Y Chen, G Wang, M Abdalla… - Science translational …, 2022 - science.org
Glioblastoma multiforme (GBM) remains incurable despite aggressive implementation of
multimodal treatments after surgical debulking. Almost all patients with GBM relapse within a …

Tumor-derived exosomes deliver the tumor suppressor miR-3591-3p to induce M2 macrophage polarization and promote glioma progression

M Li, H Xu, Y Qi, Z Pan, B Li, Z Gao, R Zhao, H Xue… - Oncogene, 2022 - nature.com
Exosomes can selectively secrete harmful metabolic substances from cells to maintain
cellular homeostasis, and complex crosstalk occurs between exosomes and tumor …

Engineered extracellular vesicle-delivered CRISPR/Cas9 for radiotherapy sensitization of glioblastoma

X Liu, Z Cao, W Wang, C Zou, Y Wang, L Pan, B Jia… - ACS …, 2023 - ACS Publications
Radiotherapy is a mainstay of glioblastoma (GBM) treatment; however, the development of
therapeutic resistance has hampered the efficacy of radiotherapy, suggesting that additional …

Impact of PEGylated liposomal doxorubicin and carboplatin combination on glioblastoma

M Ghaferi, A Raza, M Koohi, W Zahra, A Akbarzadeh… - Pharmaceutics, 2022 - mdpi.com
Glioblastoma is an incurable cancer with a 5-year survival chance of less than 5%.
Chemotherapy is a therapeutic approach to treating the disease; however, due to the …

[HTML][HTML] Versatile metal-phenolic network nanoparticles for multitargeted combination therapy and magnetic resonance tracing in glioblastoma

Y Zhang, K Xi, X Fu, H Sun, H Wang, D Yu, Z Li, Y Ma… - Biomaterials, 2021 - Elsevier
Glioblastoma multiforme (GBM) is a common malignancy of the central nervous system, but
conventional treatments yield unsatisfactory results. Although innovative therapeutic …

Nanotechnology meets glioblastoma multiforme: Emerging therapeutic strategies

D Liu, X Dai, L Ye, H Wang, H Qian… - Wiley …, 2023 - Wiley Online Library
Glioblastoma multiforme (GBM) represents the most common and fatal form of primary
invasive brain tumors as it affects a great number of patients each year and has a median …

Advances in diagnostic tools and therapeutic approaches for gliomas: A comprehensive review

G Thenuwara, J Curtin, F Tian - Sensors, 2023 - mdpi.com
Gliomas, a prevalent category of primary malignant brain tumors, pose formidable clinical
challenges due to their invasive nature and limited treatment options. The current …

Rationally designed drug delivery systems for the local treatment of resected glioblastoma

C Bastiancich, A Malfanti, V Préat, R Rahman - Advanced drug delivery …, 2021 - Elsevier
Glioblastoma (GBM) is a particularly aggressive brain cancer associated with high
recurrence and poor prognosis. The standard of care, surgical resection followed by …