Lignans have long been known for their abundant therapeutic properties due to their
polyphenolic structure. Linseed is the richest plant source of lignans and has been studied …

The advancement in high-throughput sequencing analysis and the evaluation of chromatin
state maps have revealed that eukaryotic cells produce many non-coding transcripts/RNAs …

Abstract Benzo [a] pyrene (BaP) can cause hepatorenal toxicity. Secoisolariciresinol
diglucoside (SDG), a polyphenolic compound present in flaxseed, has shown a variety of …

Background Secoisolariciresinol diglucoside (SDG), the main lignan in whole grain
flaxseed, is a potent antioxidant and free radical scavenger with known radioprotective …

Background Myeloperoxidase (MPO) generates hypochlorous acid (HOCl) during
inflammation and infection. We showed that secoisolariciresinol diglucoside (SDG) …

Abstract Secoisolariciresinol diglucosides (SDGs)(S, S)-SDG-1 (major isomer in flaxseed)
and (R, R)-SDG-2 (minor isomer in flaxseed) were synthesized from vanillin via …

Aims Inflammatory bowel disease, a chronic inflammatory disorder of the intestinal mucosa,
is a clinical presentation of Crohn's disease and ulcerative colitis (UC). This study …

Secoisolariciresinol diglucoside (SDG) is the major lignan in wholegrain flaxseed. However,
extraction methods are complex and are associated with low yield and high costs. Using a …

Due to substantial morbidity and high complication rate of diabetes mellitus, which is
considered as the third killer in the world, a search for the effective blockade of the …

Nutraceuticals claim physiological benefits, ie, why they are called alternatives to
pharmaceuticals. They are formulated from active components isolated either from plant …