Correlation between the BRAF V600E Mutation and Tumor Invasiveness in Papillary Thyroid Carcinomas Smaller than 20 Millimeters: Analysis of 1060 Cases
F Basolo, L Torregrossa, R Giannini… - The Journal of …, 2010 - academic.oup.com
Context: Evaluation of the degree of neoplastic infiltration beyond the thyroid capsule
remains a unique parameter that can be evaluated by histopathological examination to label …
remains a unique parameter that can be evaluated by histopathological examination to label …
Clinical characteristics and outcome of patients with lung cancer harboring BRAF mutations
C Tissot, S Couraud, R Tanguy, PP Bringuier, N Girard… - Lung cancer, 2016 - Elsevier
Introduction BRAF (v-Raf murine sarcoma viral oncogene homolog B) mutations are
identified in approximately 2% of non-small cell lung cancer (NSCLC). Because of the rarity …
identified in approximately 2% of non-small cell lung cancer (NSCLC). Because of the rarity …
Targeting vascular endothelial growth factor receptor in thyroid cancer: the intracellular and extracellular implications
SM Keefe, MA Cohen, MS Brose - Clinical Cancer Research, 2010 - AACR
Our understanding of the molecular pathophysiology of differentiated thyroid cancer (DTC)
has developed considerably over the last 10 years. Aberrant signaling through B-Raf and …
has developed considerably over the last 10 years. Aberrant signaling through B-Raf and …
What if many follicular variant papillary thyroid carcinomas are not malignant? A review of follicular variant papillary thyroid carcinoma and a proposal for a new …
GH Daniels - Endocrine Practice, 2011 - Elsevier
Objectives To review the relevant literature concerning follicular variant of papillary thyroid
carcinoma (FVPTC) with an emphasis on the heterogeneity of this disorder and to propose a …
carcinoma (FVPTC) with an emphasis on the heterogeneity of this disorder and to propose a …
A Novel Complex BRAF Mutation Detected in a Solid Variant of Papillary Thyroid Carcinoma
S Chiosea, M Nikiforova, H Zuo, J Ogilvie, M Gandhi… - Endocrine …, 2009 - Springer
BRAF gene mutations are identified in about 45% of papillary thyroid carcinomas (PTC) and
represent the most common genetic event in this tumor. Here, we report a case of PTC, solid …
represent the most common genetic event in this tumor. Here, we report a case of PTC, solid …
Papillary thyroid carcinoma with rare exon 15 BRAF mutation has indolent behavior: a single-institution experience
L Torregrossa, D Viola, E Sensi… - The Journal of …, 2016 - academic.oup.com
Context: Approximately 40% of papillary thyroid carcinomas (PTCs) harbor the BRAF V600E
mutation, which is significantly associated with the advanced clinicopathological features of …
mutation, which is significantly associated with the advanced clinicopathological features of …
A comprehensive analysis identifies BRAF hotspot mutations associated with gliomas with peculiar epithelial morphology
R Hatae, N Hata, SO Suzuki, K Yoshimoto… - …, 2017 - Wiley Online Library
Brain tumors harbor various BRAF alterations, the vast majority of which are the BRAF
kinase‐activating V600E mutation. BRAF mutations are most frequently detected in certain …
kinase‐activating V600E mutation. BRAF mutations are most frequently detected in certain …
[HTML][HTML] Significant Improvement in Detecting BRAF, KRAS, and EGFR Mutations Using Next-Generation Sequencing as Compared with FDA-Cleared Kits
W Ma, S Brodie, S Agersborg, VA Funari… - Molecular diagnosis & …, 2017 - Springer
Introduction We compared mutations detected in EGFR, KRAS, and BRAF genes using next-
generation sequencing (NGS) and confirmed by Sanger sequencing with mutations that …
generation sequencing (NGS) and confirmed by Sanger sequencing with mutations that …
[HTML][HTML] Clinicopathological features of rare BRAF mutations in Korean thyroid cancer patients
The most common BRAF mutation in thyroid cancer is c. 1799T> A (p. Val600Glu), and other
BRAF mutations are rarely reported. We investigated the clinicopathological features of …
BRAF mutations are rarely reported. We investigated the clinicopathological features of …
[HTML][HTML] BRAF mutations in thyroid tumors from an ethnically diverse group
HJ Schulten, S Salama, Z Al-Mansouri, R Alotibi… - Hereditary cancer in …, 2012 - Springer
Background The molecular etiology of thyroid carcinoma (TC) and other thyroid diseases
which may present malignant precursor lesions is not fully explored yet. The purpose of this …
which may present malignant precursor lesions is not fully explored yet. The purpose of this …