Strategies to improve the antitumor effect of immunotherapy for hepatocellular carcinoma
R Xing, J Gao, Q Cui, Q Wang - Frontiers in immunology, 2021 - frontiersin.org
Hepatocellular carcinoma (HCC), one of the most fatal malignancies in the world, is usually
diagnosed in advanced stages due to late symptom manifestation with very limited …
diagnosed in advanced stages due to late symptom manifestation with very limited …
Rationale of combination of anti-PD-1/PD-L1 antibody therapy and radiotherapy for cancer treatment
Significant technological advances in radiotherapy have been made in the past few
decades. High-precision radiotherapy has recently become popular and is contributing to …
decades. High-precision radiotherapy has recently become popular and is contributing to …
[HTML][HTML] Strategies targeting PD-L1 expression and associated opportunities for cancer combination therapy
S Yin, Z Chen, D Chen, D Yan - Theranostics, 2023 - ncbi.nlm.nih.gov
Immunotherapy has achieved great success recently and opened a new avenue for anti-
tumor treatment. Programmed cell death 1/programmed cell death ligand 1 (PD-1/PD-L1) …
tumor treatment. Programmed cell death 1/programmed cell death ligand 1 (PD-1/PD-L1) …
Radiotherapy–immunotherapy combinations–perspectives and challenges
Ionizing radiation has historically been used to treat cancer by killing tumour cells, in
particular by inducing DNA damage. This view of radiotherapy (RT) as a simple cytotoxic …
particular by inducing DNA damage. This view of radiotherapy (RT) as a simple cytotoxic …
A PD-L1 and VEGFR2 dual targeted peptide and its combination with irradiation for cancer immunotherapy
L Jiao, Q Dong, W Zhai, W Zhao, P Shi, Y Wu… - Pharmacological …, 2022 - Elsevier
Although the blockade of immune checkpoint PD-1/PD-L1 has achieved great success, the
lack of tumor-infiltrating immune cells and PD-L1 expression in the tumor microenvironment …
lack of tumor-infiltrating immune cells and PD-L1 expression in the tumor microenvironment …
Cisplatin facilitates radiation-induced abscopal effects in conjunction with PD-1 checkpoint blockade through CXCR3/CXCL10-mediated T-cell recruitment
R Luo, E Firat, S Gaedicke, E Guffart, T Watanabe… - Clinical Cancer …, 2019 - AACR
Purpose: Localized radiotherapy can cause T-cell–mediated abscopal effects on
nonirradiated metastases, particularly in combination with immune checkpoint blockade …
nonirradiated metastases, particularly in combination with immune checkpoint blockade …
The role of radiotherapy in the age of immunotherapy
With the development of immune checkpoint inhibitors, the efficacy of immunotherapy as a
cancer treatment that is effective against multiple tumor types has been established, and this …
cancer treatment that is effective against multiple tumor types has been established, and this …
Regulation of programmed death‐ligand 1 expression in response to DNA damage in cancer cells: implications for precision medicine
Abstract Anti‐programmed death‐1 (PD‐1)/programmed death‐ligand 1 (PD‐L1) therapy,
which is one of the most promising cancer therapies, is licensed for treating various tumors …
which is one of the most promising cancer therapies, is licensed for treating various tumors …
TIGIT blockade enhances tumor response to radiotherapy via a CD103+ dendritic cell-dependent mechanism
K Zhao, L Jiang, Y Si, S Zhou, Z Huang… - Cancer Immunology …, 2023 - Springer
Blockade of the T cell immunoreceptor with the immunoglobulin and immunoreceptor
tyrosine-based inhibitory motif domain (TIGIT) can enhance innate and adaptive tumor …
tyrosine-based inhibitory motif domain (TIGIT) can enhance innate and adaptive tumor …
[HTML][HTML] Nanoparticles augment the therapeutic window of RT and immunotherapy for treating cancers: pivotal role of autophagy
Immunotherapies are now emerging as an efficient anticancer therapeutic strategy. Cancer
immunotherapy utilizes the host's immune system to fight against cancer cells and has …
immunotherapy utilizes the host's immune system to fight against cancer cells and has …