miRNAs orchestration of cardiovascular diseases–Particular emphasis on diagnosis, and progression
MicroRNAs (miRNAs; miRs) are small non-coding ribonucleic acids sequences vital in
regulating gene expression. They are significant in many biological and pathological …
regulating gene expression. They are significant in many biological and pathological …
Physiological and pathophysiological roles of the KCNK3 potassium channel in the pulmonary circulation and the heart
A Saint‐Martin Willer, J Santos‐Gomes… - The Journal of …, 2023 - Wiley Online Library
Potassium channel subfamily K member 3 (KCNK3), encoded by the KCNK3 gene, is part of
the two‐pore domain potassium channel family, constitutively active at resting membrane …
the two‐pore domain potassium channel family, constitutively active at resting membrane …
microRNAs as Biomarkers of Endothelial Dysfunction and Therapeutic Target in the Pathogenesis of Atrial Fibrillation
V Desantis, MA Potenza, L Sgarra, C Nacci… - International Journal of …, 2023 - mdpi.com
The pathophysiology of atrial fibrillation (AF) may involve atrial fibrosis/remodeling and
dysfunctional endothelial activities. Despite the currently available treatment approaches …
dysfunctional endothelial activities. Despite the currently available treatment approaches …
Non-coding RNA and arrhythmias: expression, function, and molecular mechanism
Y Zeng, N Wu, Z Zhang, L Zhong, G Li, Y Li - Europace, 2023 - academic.oup.com
Arrhythmias are a class of cardiac dysfunction characterized by heart rate disturbances and
heart rhythm abnormalities, which are associated with substantial morbidity and mortality …
heart rhythm abnormalities, which are associated with substantial morbidity and mortality …
Advances in the understanding of two-pore domain TASK potassium channels and their potential as therapeutic targets
X Fan, Y Lu, G Du, J Liu - Molecules, 2022 - mdpi.com
TWIK-related acid-sensitive K+ (TASK) channels, including TASK-1, TASK-3, and TASK-5,
are important members of the two-pore domain potassium (K2P) channel family. TASK-5 is …
are important members of the two-pore domain potassium (K2P) channel family. TASK-5 is …
Non-Coding RNAs and Gut Microbiota in the Pathogenesis of Cardiac Arrhythmias: The Latest Update
N Suga, Y Ikeda, S Yoshikawa, K Taniguchi… - Genes, 2023 - mdpi.com
Non-coding RNAs (ncRNAs) are indispensable for adjusting gene expression and genetic
programming throughout development and for health as well as cardiovascular diseases …
programming throughout development and for health as well as cardiovascular diseases …
Therapeutic overexpression of miR-92a-2-5p ameliorated cardiomyocyte oxidative stress injury in the development of diabetic cardiomyopathy
M Yu, Y Sun, X Shan, F Yang, G Chu, Q Chen… - Cellular & Molecular …, 2022 - Springer
Background Diabetic cardiomyopathy (DCM) results from pathological changes in cardiac
structure and function caused by diabetes. Excessive oxidative stress is an important feature …
structure and function caused by diabetes. Excessive oxidative stress is an important feature …
Noncoding RNAs as key regulators for cardiac development and cardiovascular diseases
S Kawaguchi, B Moukette, T Hayasaka… - Journal of …, 2023 - mdpi.com
Noncoding RNAs (ncRNAs) play fundamental roles in cardiac development and
cardiovascular diseases (CVDs), which are a major cause of morbidity and mortality. With …
cardiovascular diseases (CVDs), which are a major cause of morbidity and mortality. With …
Circulating miR-451a expression may predict recurrence in atrial fibrillation patients after catheter pulmonary vein ablation
R Lage, M Cebro-Márquez, ME Vilar-Sánchez… - Cells, 2023 - mdpi.com
Atrial fibrillation is the most prevalent tachyarrhythmia in clinical practice, with very high
cardiovascular morbidity and mortality with a high-cost impact in health systems. Currently, it …
cardiovascular morbidity and mortality with a high-cost impact in health systems. Currently, it …
Exploring the involvement of TASK-1 in the control of isolated rat right atrium function from healthy animals and an experimental model of monocrotaline-induced …
JL Teixeira-Fonseca, JV Joviano-Santos… - Naunyn-Schmiedeberg's …, 2023 - Springer
The TASK-1 channel belongs to the two-pore domain potassium channel family. It is
expressed in several cells of the heart, including the right atrial (RA) cardiomyocytes and the …
expressed in several cells of the heart, including the right atrial (RA) cardiomyocytes and the …