Mechanisms of microtubule organization in differentiated animal cells
A Akhmanova, LC Kapitein - Nature Reviews Molecular Cell Biology, 2022 - nature.com
Microtubules are polarized cytoskeletal filaments that serve as tracks for intracellular
transport and form a scaffold that positions organelles and other cellular components and …
transport and form a scaffold that positions organelles and other cellular components and …
Conservation of oocyte development in germline cysts from Drosophila to mouse
Recent studies show that pre-follicular mouse oogenesis takes place in germline cysts,
highly conserved groups of oogonial cells connected by intercellular bridges that develop as …
highly conserved groups of oogonial cells connected by intercellular bridges that develop as …
Polarized microtubule remodeling transforms the morphology of reactive microglia and drives cytokine release
Microglial reactivity is a pathological hallmark in many neurodegenerative diseases. During
stimulation, microglia undergo complex morphological changes, including loss of their …
stimulation, microglia undergo complex morphological changes, including loss of their …
O‐GlcNAcylation Regulates Centrosome Behavior and Cell Polarity to Reduce Pulmonary Fibrosis and Maintain the Epithelial Phenotype
F Yu, S Yang, H Ni, D Heng, X Wu, M Yang… - Advanced …, 2023 - Wiley Online Library
O‐GlcNAcylation functions as a cellular nutrient and stress sensor and participates in almost
all cellular processes. However, it remains unclear whether O‐GlcNAcylation plays a role in …
all cellular processes. However, it remains unclear whether O‐GlcNAcylation plays a role in …
Principles of organelle positioning in motile and non-motile cells
J Kroll, J Renkawitz - EMBO reports, 2024 - embopress.org
Cells are equipped with asymmetrically localised and functionally specialised components,
including cytoskeletal structures and organelles. Positioning these components to specific …
including cytoskeletal structures and organelles. Positioning these components to specific …
Microtubule organization is essential for maintaining cellular morphology and function
L Huang, Y Peng, X Tao, X Ding, R Li… - Oxidative medicine …, 2022 - Wiley Online Library
Microtubules (MTs) are highly dynamic polymers essential for a wide range of cellular
physiologies, such as acting as directional railways for intracellular transport and position …
physiologies, such as acting as directional railways for intracellular transport and position …
Self-organization of cellular units
TJ Mitchison, CM Field - Annual review of cell and …, 2021 - annualreviews.org
The purpose of this review is to explore self-organizing mechanisms that pattern
microtubules (MTs) and spatially organize animal cell cytoplasm, inspired by recent …
microtubules (MTs) and spatially organize animal cell cytoplasm, inspired by recent …
[HTML][HTML] Microglia reactivity entails microtubule remodeling from acentrosomal to centrosomal arrays
Microglia reactivity entails a large-scale remodeling of cellular geometry, but the behavior of
the microtubule cytoskeleton during these changes remains unexplored. Here we show that …
the microtubule cytoskeleton during these changes remains unexplored. Here we show that …
[HTML][HTML] ER and Golgi trafficking in axons, dendrites, and glial processes
Both neurons and glia in mammalian brains are highly ramified. Neurons form complex
neural networks using axons and dendrites. Axons are long with few branches and form pre …
neural networks using axons and dendrites. Axons are long with few branches and form pre …
Microtubule anchoring: attaching dynamic polymers to cellular structures
C Vineethakumari, J Lüders - Frontiers in Cell and Developmental …, 2022 - frontiersin.org
Microtubules are dynamic, filamentous polymers composed of α-and β-tubulin. Arrays of
microtubules that have a specific polarity and distribution mediate essential processes such …
microtubules that have a specific polarity and distribution mediate essential processes such …